Alterations of global DNA methylation and DNA methyltransferase expression in T and B lymphocytes from patients with newly diagnosed autoimmune thyroid …
Q Guo, D Wu, H Yu, J Bao, S Peng, Z Shan, H Guan… - Thyroid, 2018 - liebertpub.com
Background: Dysregulated DNA methylation in lymphocytes has been linked to autoimmune
disorders. The aims of this study were to identify global DNA methylation patterns in patients …
disorders. The aims of this study were to identify global DNA methylation patterns in patients …
Deciphering the role of DNA methylation in multiple sclerosis: emerging issues
M Sokratous, E Dardiotis, Z Tsouris, E Bellou… - Autoimmunity …, 2016 - Springer
Multiple sclerosis (MS) is an autoimmune inflammatory and neurodegenerative disease of
the central nervous system that involves several not yet fully elucidated pathophysiologic …
the central nervous system that involves several not yet fully elucidated pathophysiologic …
Mini-review of DNA Methylation Detection Techniques and Their Potential Applications in Disease Diagnosis, Prognosis, and Treatment
H Zhang, L Liu, M Li - ACS sensors, 2024 - ACS Publications
DNA methylation is the dominant epigenetic mechanism for regulating gene expression in
mammals, playing crucial roles in development, differentiation, and tissue homeostasis …
mammals, playing crucial roles in development, differentiation, and tissue homeostasis …
DNA methylation alterations as therapeutic prospects in thyroid cancer
K Zhang, C Li, J Liu, X Tang, Z Li - Journal of endocrinological …, 2019 - Springer
Background Thyroid cancer is one of the most common endocrine malignancies. Although
the 10-year survival rate of differentiated thyroid cancer (DTC) is about 90% after …
the 10-year survival rate of differentiated thyroid cancer (DTC) is about 90% after …
[HTML][HTML] Accumulated promoter methylation as a potential biomarker for esophageal cancer
X Peng, H Xue, L Lü, P Shi, J Wang, J Wang - Oncotarget, 2016 - pmc.ncbi.nlm.nih.gov
We performed a two-stage molecular epidemiological study to explore DNA methylation
profiles for potential biomarkers of esophageal squamous cell carcinoma (ESCC) in a …
profiles for potential biomarkers of esophageal squamous cell carcinoma (ESCC) in a …
High-throughput DNA methylation analysis in ITP confirms NOTCH1 hypermethylation through the Th1 and Th2 cell differentiation pathways
S Liu, H Qu, R Sun, D Yuan, X Sui, N Shan - International …, 2022 - Elsevier
Background Immune thrombocytopenia (ITP) is a prevalent autoimmune disease with a
complex aetiology where DNA methylation changes are becoming triggers. Method To …
complex aetiology where DNA methylation changes are becoming triggers. Method To …
DNA methylation down‐regulates integrin β4 expression in asthmatic airway epithelial cells
M Wu, Y Yang, L Yuan, M Yang, L Wang… - Clinical & …, 2020 - Wiley Online Library
Abstract Background Integrin β4 (ITGB4) is a hemi‐desmosome protein which is
downregulated in the airway epithelial cells of asthma patients. The proximal promoters and …
downregulated in the airway epithelial cells of asthma patients. The proximal promoters and …
Gene profiling of Epstein-Barr Virus and human endogenous retrovirus in peripheral blood mononuclear cells of SLE patients: immune response implications
Systemic lupus erythematosus (SLE) is a multifactorial disease characterized by the
convergence of genetic, immunological, and viral elements resulting in a complex …
convergence of genetic, immunological, and viral elements resulting in a complex …
Epigenetic underpinnings of developmental immunotoxicity and autoimmune disease
SJ Blossom, KM Gilbert - Current opinion in toxicology, 2018 - Elsevier
The concordance rate for developing autoimmune disease in identical twins is around 50%
demonstrating that gene and environmental interactions contribute to disease etiology. The …
demonstrating that gene and environmental interactions contribute to disease etiology. The …
[Retracted] DNMT1‐Mediated DNA Methylation Targets CDKN2B to Promote the Repair of Retinal Ganglion Cells in Streptozotocin‐Induced Mongolian Gerbils during …
X Wang, J Zhang, Y Liao, Y Jin, X Yu… - … Methods in Medicine, 2022 - Wiley Online Library
Objective. DNA methylation played a vital role in the progression of diabetic retinopathy. In
this study, we aimed to explore the role of DNA cytosine‐5‐methyltransferase 1 (DNMT1) in …
this study, we aimed to explore the role of DNA cytosine‐5‐methyltransferase 1 (DNMT1) in …