Over the past several decades, there has been an ever-increasing demand for organ
transplants. However, there is a severe shortage of donor organs, and as a result of the …

This review highlights recent trends towards the development of in vitro multicellular systems
with definite architectures, or “organs on chips”. First, the chemical composition and …

Background: Tissue engineering enables the generation of functional human cardiac tissue
with cells derived in vitro in combination with biocompatible materials. Human-induced …

For 3D bioprinted tissues to be scaled-up to clinically relevant sizes, effective
prevascularisation strategies are required to provide the necessary nutrients for normal …

Medical patches have been widely explored and applied in various medical fields,
especially in wound healing, tissue engineering, and other biomedical areas. Benefiting …

Functional and perfusable vascular network formation is critical to ensure the long-term
survival and functionality of engineered tissues after their transplantation. Although several …

Fibrin, a natural hydrogel, is the end product of the physiological blood coagulation cascade
and naturally involved in wound healing. Beyond its role in hemostasis, it acts as a local …

The primary function of vascular networks is to transport blood and deliver oxygen and
nutrients to tissues, which occurs at the interface of the microvasculature. Therefore, the …

Vascular tissue engineering has the potential to make a significant impact on the treatment
of a wide variety of medical conditions, including providing in vitro generated vascularized …

As the only striated muscle tissues in the body, skeletal and cardiac muscle share numerous
structural and functional characteristics, while exhibiting vastly different size and …