The relationship between cannabis and schizophrenia: a genetically informed perspective
Abstract Background and Aims While epidemiological studies support a role for heavy, high‐
potency cannabis use on first‐episode psychosis, genetic models of causation suggest …
potency cannabis use on first‐episode psychosis, genetic models of causation suggest …
Pervasive downward bias in estimates of liability-scale heritability in genome-wide association study meta-analysis: a simple solution
Background Single nucleotide polymorphism–based heritability is a fundamental quantity in
the genetic analysis of complex traits. For case-control phenotypes, for which the continuous …
the genetic analysis of complex traits. For case-control phenotypes, for which the continuous …
Associations between cannabis use, cannabis use disorder, and mood disorders: longitudinal, genetic, and neurocognitive evidence
Rationale Cannabis use among people with mood disorders increased in recent years.
While comorbidity between cannabis use, cannabis use disorder (CUD), and mood …
While comorbidity between cannabis use, cannabis use disorder (CUD), and mood …
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes
Tobacco use disorder (TUD) is the most prevalent substance use disorder in the world.
Genetic factors influence smoking behaviours and although strides have been made using …
Genetic factors influence smoking behaviours and although strides have been made using …
[HTML][HTML] Genome-wide association study of problematic opioid prescription use in 132,113 23andMe research participants of European ancestry
S Sanchez-Roige, P Fontanillas, MV Jennings… - Molecular …, 2021 - nature.com
The growing prevalence of opioid use disorder (OUD) constitutes an urgent health crisis.
Ample evidence indicates that risk for OUD is heritable. As a surrogate (or proxy) for OUD …
Ample evidence indicates that risk for OUD is heritable. As a surrogate (or proxy) for OUD …
[HTML][HTML] Smoking is significantly associated with increased risk of COVID-19 and other respiratory infections
DB Rosoff, J Yoo, FW Lohoff - Communications biology, 2021 - nature.com
Observational studies suggest smoking, cannabis use, alcohol consumption, and substance
use disorders (SUDs) may impact risk for respiratory infections, including coronavirus 2019 …
use disorders (SUDs) may impact risk for respiratory infections, including coronavirus 2019 …
The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study
Background The relationship between psychotic disorders and cannabis use is heavily
debated. Shared underlying genetic risk is one potential explanation. We investigated the …
debated. Shared underlying genetic risk is one potential explanation. We investigated the …
Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains
Attention deficit hyperactivity disorder (ADHD) is a prevalent childhood psychiatric disorder,
with a major genetic component. Here we present a GWAS meta-analysis of ADHD …
with a major genetic component. Here we present a GWAS meta-analysis of ADHD …
The Collaborative Study on the Genetics of Alcoholism: Overview
A Agrawal, SJ Brislin, KK Bucholz… - Genes, Brain and …, 2023 - Wiley Online Library
Alcohol use disorders (AUD) are commonly occurring, heritable and polygenic disorders
with etiological origins in the brain and the environment. To outline the causes and …
with etiological origins in the brain and the environment. To outline the causes and …
The collaborative study on the genetics of alcoholism: Sample and clinical data
The collaborative study on the genetics of alcoholism (COGA) is a multi‐site,
multidisciplinary project with the goal of identifying how genes are involved in alcohol use …
multidisciplinary project with the goal of identifying how genes are involved in alcohol use …