[HTML][HTML] Epigenetic modifications affect the rate of spontaneous mutations in a pathogenic fungus
Mutations are the source of genetic variation and the substrate for evolution. Genome-wide
mutation rates appear to be affected by selection and are probably adaptive. Mutation rates …
mutation rates appear to be affected by selection and are probably adaptive. Mutation rates …
Using structural variants to understand the ecological and evolutionary dynamics of fungal plant pathogens
FE Hartmann - New Phytologist, 2022 - Wiley Online Library
Deletions, duplications, insertions, inversions and translocations are commonly referred to
as structural variants (SVs). Fungal plant pathogens have compact genomes, facilitating the …
as structural variants (SVs). Fungal plant pathogens have compact genomes, facilitating the …
Hiding in plain sight: Genome-wide recombination and a dynamic accessory genome drive diversity in Fusarium oxysporum f.sp. ciceris
Understanding the origins of variation in agricultural pathogens is of fundamental interest
and practical importance, especially for diseases that threaten food security. Fusarium …
and practical importance, especially for diseases that threaten food security. Fusarium …
[HTML][HTML] A 19-isolate reference-quality global pangenome for the fungal wheat pathogen Zymoseptoria tritici
Background The gene content of a species largely governs its ecological interactions and
adaptive potential. A species is therefore defined by both core genes shared between all …
adaptive potential. A species is therefore defined by both core genes shared between all …
[HTML][HTML] The need for speed: compartmentalized genome evolution in filamentous phytopathogens
More than 10 years of extensive efforts since the dawn of highthroughput sequencing have
resulted in a wealth of genome data for filamentous plant pathogens and have led to several …
resulted in a wealth of genome data for filamentous plant pathogens and have led to several …
[HTML][HTML] Destabilization of chromosome structure by histone H3 lysine 27 methylation
M Möller, K Schotanus, JL Soyer, J Haueisen… - PLoS …, 2019 - journals.plos.org
Chromosome and genome stability are important for normal cell function as instability often
correlates with disease and dysfunction of DNA repair mechanisms. Many organisms …
correlates with disease and dysfunction of DNA repair mechanisms. Many organisms …
[HTML][HTML] Combined pangenomics and transcriptomics reveals core and redundant virulence processes in a rapidly evolving fungal plant pathogen
H Chen, R King, D Smith, C Bayon, T Ashfield… - BMC biology, 2023 - Springer
Background Studying genomic variation in rapidly evolving pathogens potentially enables
identification of genes supporting their “core biology”, being present, functional and …
identification of genes supporting their “core biology”, being present, functional and …
[HTML][HTML] Genomic rearrangements generate hypervariable mini-chromosomes in host-specific isolates of the blast fungus
T Langner, A Harant, LB Gomez-Luciano… - PLoS …, 2021 - journals.plos.org
Supernumerary mini-chromosomes–a unique type of genomic structural variation–have
been implicated in the emergence of virulence traits in plant pathogenic fungi. However, the …
been implicated in the emergence of virulence traits in plant pathogenic fungi. However, the …
Extraordinary genome instability and widespread chromosome rearrangements during vegetative growth
The ability to rapidly adapt to changing environments is crucial for the success of pathogens
infecting plants and animals. In some eukaryotic pathogens, rapid evolution can be …
infecting plants and animals. In some eukaryotic pathogens, rapid evolution can be …