Pathogenesis of African swine fever in domestic pigs and European wild boar

S Blome, C Gabriel, M Beer - Virus research, 2013 - Elsevier
African swine fever (ASF) is among the most important viral diseases that can affect
domestic and feral pigs. Both clinical signs and pathomorphological changes vary …

Transcriptome view of a killer: African swine fever virus

G Cackett, M Sýkora, F Werner - Biochemical Society …, 2020 - portlandpress.com
African swine fever virus (ASFV) represents a severe threat to global agriculture with the
world's domestic pig population reduced by a quarter following recent outbreaks in Europe …

Modern adjuvants do not enhance the efficacy of an inactivated African swine fever virus vaccine preparation

S Blome, C Gabriel, M Beer - Vaccine, 2014 - Elsevier
African swine fever (ASF) is among the most devastating viral diseases of pigs. In recent
years, the disease has spread alarmingly. Despite intensive research activities, promising …

Related strains of African swine fever virus with different virulence: genome comparison and analysis

R Portugal, J Coelho, D Hoeper… - Journal of General …, 2015 - microbiologyresearch.org
Two strains of African swine fever virus (ASFV), the high-virulence Lisboa60 (L60) and the
low-virulence NH/P68 (NHV), which have previously been used in effective immunization …

Role of African swine fever virus proteins EP153R and EP402R in reducing viral persistence in blood and virulence in pigs infected with BeninΔDP148R

V Petrovan, A Rathakrishnan, M Islam… - Journal of …, 2022 - Am Soc Microbiol
The limited knowledge on the role of many of the approximately 170 proteins encoded by
African swine fever virus restricts progress toward vaccine development. Previously, the …

African swine fever virus controls the host transcription and cellular machinery of protein synthesis

EG Sánchez, A Quintas, M Nogal, A Castelló, Y Revilla - Virus research, 2013 - Elsevier
Throughout a viral infection, the infected cell reprograms the gene expression pattern in
order to establish a satisfactory antiviral response. African swine fever virus (ASFV), like …

[HTML][HTML] African swine fever virus CD2v protein induces β-interferon expression and apoptosis in swine peripheral blood mononuclear cells

S Chaulagain, GA Delhon, S Khatiwada, DL Rock - Viruses, 2021 - mdpi.com
African swine fever (ASF) is a hemorrhagic disease of swine characterized by massive
lymphocyte depletion in lymphoid tissues due to the apoptosis of B and T cells, a process …

[HTML][HTML] Transcription termination and readthrough in African swine fever virus

G Cackett, M Sýkora, R Portugal, C Dulson… - Frontiers in …, 2024 - frontiersin.org
Introduction African swine fever virus (ASFV) is a nucleocytoplasmic large DNA virus
(NCLDV) that encodes its own host-like RNA polymerase (RNAP) and factors required to …

Modulation of type I interferon signaling by African swine fever virus (ASFV) of different virulence L60 and NHV in macrophage host cells

R Portugal, A Leitão, C Martins - Veterinary microbiology, 2018 - Elsevier
ASFV causes an important disease of domestic swine and wild boar. Currently no vaccine is
available, highlighting the necessity to understand ASFV modulation of innate immune …

[HTML][HTML] African swine fever virus ORF P1192R codes for a functional type II DNA topoisomerase

J Coelho, C Martins, F Ferreira, A Leitao - Virology, 2015 - Elsevier
Topoisomerases modulate the topological state of DNA during processes, such as
replication and transcription, that cause overwinding and/or underwinding of the DNA …