Impaired wound healing is one of the unsolved problems of modern medicine, affecting
patients' quality of life and causing serious economic losses. Impaired wound healing can …

Venous leg ulcers, diabetic foot ulcers, and pressure ulcers are complex chronic wounds
with multifactorial etiologies that are associated with high patient morbidity and mortality …

Stringent spatiotemporal regulation of the wound healing process involving multiple cell
types is associated with epigenetic mechanisms of gene regulation, such as DNA …

体表慢性难愈合创面的诊断和治疗一直充满着挑战, 对医疗和社会造成巨大负担.
利用高通量测序技术结合组学分析可以揭示慢性创面形成的潜在机制, 识别与慢性创面诊断 …

Annexin A1, a well-known endogenous anti-inflammatory mediator, plays a critical role in a
variety of pathological processes. Fibrosis is described by a failure of tissue regeneration …

转化生长因子β/Smad 信号通路与瘢痕疙瘩的靶向治疗 Page 1 Chinese Journal of Tissue
Engineering Research|Vol 28|No.16|June 2024|2619 中国组织工程研究 Chinese Journal of …

Morphea and lichen sclerosis et atrophicus (LSA) are two distinct immune-mediated
diseases with a dominant presentation of dermal fibrosis and sclerosis. The two diseases …

Diabetic foot ulcers (DFUs), a prevalent complication of diabetes, constitute a major medical
challenge with a critical need for development of cell‐based therapies. We previously …

The hepatic extracellular matrix (ECM) is most accurately depicted as a dynamic
compartment that comprises a diverse range of players that work bi-directionally with hepatic …

Myocardial fibrosis can induce cardiac dysfunction and remodeling. Great attention has
been paid to traditional chinese medicine (TCM)'s effectiveness in treating MF. Radix …