[HTML][HTML] Pharmacogenetics of toxicity of 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients
K Tecza, J Pamula-Pilat, J Lanuszewska… - Oncotarget, 2018 - ncbi.nlm.nih.gov
The differences in patients' response to the same medication, toxicity included, are one of
the major problems in breast cancer treatment. Chemotherapy toxicity makes a significant …
the major problems in breast cancer treatment. Chemotherapy toxicity makes a significant …
Impact of ABC single nucleotide polymorphisms upon the efficacy and toxicity of induction chemotherapy in acute myeloid leukemia
JE Megías-Vericat, P Montesinos, MJ Herrero… - Leukemia & …, 2017 - Taylor & Francis
Anthracycline uptake could be affected by efflux pumps of the ABC family. The influence of 7
SNPs of ABC genes was evaluated in 225 adult de novo acute myeloid leukemia (AML) …
SNPs of ABC genes was evaluated in 225 adult de novo acute myeloid leukemia (AML) …
Genetic risk factors for clozapine-induced neutropenia and agranulocytosis in a Dutch psychiatric population
K Van Der Weide, H Loovers, K Pondman… - The …, 2017 - nature.com
Prescription of clozapine is complicated by the occurrence of clozapine-induced reduction of
neutrophils. The aim of this study was to identify genetic risk factors in a population of 310 …
neutrophils. The aim of this study was to identify genetic risk factors in a population of 310 …
Advances and challenges in hereditary cancer pharmacogenetics
I Cascorbi, AN Werk - Expert Opinion on Drug Metabolism & …, 2017 - Taylor & Francis
Introduction: Cancer pharmacogenetics usually considers tumor-specific targets. However,
hereditary genetic variants may interfere with the pharmacokinetics of antimetabolites and …
hereditary genetic variants may interfere with the pharmacokinetics of antimetabolites and …
转染miRNA27a 抑制物对卵巢癌耐药细胞系顺铂敏感性的研究
高慧 - 山东医学高等专科学校学报, 2015 - cqvip.com
目的研究下调miRNA27a 对卵巢癌细胞系skov3/DDP 顺铂耐药性的影响.
方法培养卵巢癌细胞系skov3, 使用顺铂诱导, 建立卵巢癌顺铂耐药细胞系skov3/DD, MTT …
方法培养卵巢癌细胞系skov3, 使用顺铂诱导, 建立卵巢癌顺铂耐药细胞系skov3/DD, MTT …
ABC 转运蛋白基因多态性与晚期非小细胞肺癌铂类药物化疗的相关性
乔荣， 吴文婷， 卢大儒， 韩宝惠 - 临床与病理杂志, 2016 - cqvip.com
目的: 研究ABC 转运蛋白基因多态性与晚期含铂方案化疗的非小细胞肺癌(non-small cell lung
cancer, NSCLC) 患者化疗敏感性和耐受性的关系. 方法: 经病理学确诊的III/IV 期NSCLC …
cancer, NSCLC) 患者化疗敏感性和耐受性的关系. 方法: 经病理学确诊的III/IV 期NSCLC …
[PDF][PDF] Does the MDR1 C34354T polymorphism influence the occurrence of nausea and sexual dysfunction after paroxetine treatment in the Slovak setting?
Z Vančová, J Dragašek, M Čižmáriková - European …, 2019 - ecnp.eu
Background As the prevalence and severity of side effects follow interindividual variations, it
is reasonable to hypothesize a genetic basis for drug tolerability [10]. Several studies have …
is reasonable to hypothesize a genetic basis for drug tolerability [10]. Several studies have …