The controversial role of homocysteine in neurology: from labs to clinical practice
R Moretti, P Caruso - International journal of molecular sciences, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing amino acid that is generated during methionine
metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin …
metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin …
Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects
HJ Blom, Y Smulders - Journal of inherited metabolic disease, 2011 - Springer
This overview addresses homocysteine and folate metabolism. Its functions and complexity
are described, leading to explanations why disturbed homocysteine and folate metabolism …
are described, leading to explanations why disturbed homocysteine and folate metabolism …
Epigenome in early mammalian development: inheritance, reprogramming and establishment
Q Xu, W Xie - Trends in cell biology, 2018 - cell.com
Drastic epigenetic reprogramming takes place during preimplantation development, leading
to the conversion of terminally differentiated gametes to a totipotent embryo. Deficiencies in …
to the conversion of terminally differentiated gametes to a totipotent embryo. Deficiencies in …
DNA hypomethylation and human diseases
AS Wilson, BE Power, PL Molloy - … et Biophysica Acta (BBA)-Reviews on …, 2007 - Elsevier
Changes in human DNA methylation patterns are an important feature of cancer
development and progression and a potential role in other conditions such as …
development and progression and a potential role in other conditions such as …
Environmental epigenetics and its implication on disease risk and health outcomes
SM Ho, A Johnson, P Tarapore, V Janakiram… - ILAR …, 2012 - academic.oup.com
This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …
and health outcomes. Major epigenetic events, such as histone modifications, DNA …
Effects of Particulate Matter on Genomic DNA Methylation Content and iNOS Promoter Methylation
L Tarantini, M Bonzini, P Apostoli… - Environmental …, 2009 - ehp.niehs.nih.gov
Background Altered patterns of gene expression mediate the effects of particulate matter
(PM) on human health, but mechanisms through which PM modifies gene expression are …
(PM) on human health, but mechanisms through which PM modifies gene expression are …
Cellular and molecular basis for endometriosis-associated infertility
Endometriosis is a gynecological disease characterized by the presence of endometrial
glandular epithelial and stromal cells growing in the extra-uterine environment. The disease …
glandular epithelial and stromal cells growing in the extra-uterine environment. The disease …
Impacts of epigenetic processes on the health and productivity of livestock
M Wang, EM Ibeagha-Awemu - Frontiers in Genetics, 2021 - frontiersin.org
The dynamic changes in the epigenome resulting from the intricate interactions of genetic
and environmental factors play crucial roles in individual growth and development …
and environmental factors play crucial roles in individual growth and development …
Folic acid, methylation and neural tube closure in humans
HJ Blom - Birth Defects Research Part A: Clinical and Molecular …, 2009 - Wiley Online Library
This review provides a brief description of folate use and folic acid metabolism in relation to
neural tube defect (NTD) risk. First, a meta‐analysis of reduction in NTD recurrence and …
neural tube defect (NTD) risk. First, a meta‐analysis of reduction in NTD recurrence and …
Genome-wide profiling of DNA methylation provides insights into epigenetic regulation of fungal development in a plant pathogenic fungus, Magnaporthe oryzae
DNA methylation is an important epigenetic modification that regulates development of
plants and mammals. To investigate the roles of DNA methylation in fungal development, we …
plants and mammals. To investigate the roles of DNA methylation in fungal development, we …