Bacterial biofilm formation involves signaling and regulatory pathways that control the
transition from motile to sessile lifestyle, production of extracellular polymeric matrix, and …

Highlights•Phage-host interactions have mostly been studied one-by-one using few old
models.•Systematic approaches reveal new molecular mechanisms of phage-host …

At its current rate, the rise of antimicrobial-resistant (AMR) infections is predicted to paralyze
our industries and healthcare facilities while becoming the leading global cause of loss of …

The bio‐based production of added‐value compounds (with applications as
pharmaceuticals, biofuels, food ingredients, and building blocks) using bacterial platforms is …

Food contamination caused by foodborne pathogens is one of the most important concerns
in public health worldwide, and accounts for a significant portion of food loss every year. The …

Staphylococcus epidermidis is a ubiquitous human commensal skin bacterium that is also
one of the most prevalent nosocomial pathogens. The genetic factors underlying this …

CRISPR screening, including CRISPR interference (CRISPRi) and CRISPR-knockout
(CRISPR-KO) screening, has become a powerful technology in the genetic screening of …

Growth decoupling can be used to optimize microbial production of biobased compounds by
inhibiting excess biomass formation and redirect carbon flux from growth to product …

Facile bacterial genome sequencing has unlocked a veritable treasure trove of novel genes
awaiting functional exploration. To make the most of this opportunity requires powerful …

Deciphering gene function is fundamental to engineering of microbiology. The clustered
regularly interspaced short palindromic repeats (CRISPR) system has been adapted for …