Longitudinal clonal tracking in humanized mice reveals sustained polyclonal repopulation of gene-modified human-HSPC despite vector integration bias

GW Suryawanshi, H Arokium, S Kim… - Stem cell research & …, 2021 - Springer
Background Current understanding of hematopoiesis is largely derived from mouse models
that are physiologically distant from humans. Humanized mice provide the most …