Kaempferol and fisetin-related signaling pathways induce apoptosis in head and neck cancer cells

R Kubina, K Krzykawski, A Dziedzic, A Kabała-Dzik - Cells, 2023 - mdpi.com
Despite the relative effectiveness of standard cancer treatment strategies, head and neck
cancer (HNC) is still considered one of the leading causes of mortality and morbidity. While …

Burden of early-onset colorectal cancer along with attributable risk factors from 1990 to 2019: a comparative study between China and other G20 countries

Q Li, M Yu, H Lv, L Zhang, Y Deng, H Yu - BMC Public Health, 2023 - Springer
Purpose The credible data about the burden of early-onset colorectal cancer (EOCRC) in
China when compared to other countries in the group of twenty (G20) remained unavailable …

Biological age and environmental risk factors for dementia and stroke: Molecular mechanisms

P Knobel, R Litke, CV Mobbs - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Since the development of antibiotics and vaccination, as well as major improvements in
public hygiene, the main risk factors for morbidity and mortality are age and chronic …

Non-pharmaceutical interventions to optimize cancer immunotherapy

M Boesch, F Baty, F Rassouli, T Kowatsch… - …, 2023 - Taylor & Francis
The traditional picture of cancer patients as weak individuals requiring maximum rest and
protection is beginning to dissolve. Too much focus on the medical side and one's own …

TRAIL-sensitizing effects of flavonoids in cancer

A Luiz-Ferreira, T Pacifico, ÁC Cruz, F Laudisi… - International Journal of …, 2023 - mdpi.com
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) represents a promising
anticancer agent, as it selectively induces apoptosis in transformed cells without altering the …

Environmental and lifestyle cancer risk factors: shaping extracellular vesicle OncomiRs and paving the path to cancer development

V Bollati, P Monti, D Biganzoli, G Marano, C Favero… - Cancers, 2023 - mdpi.com
Simple Summary In this study, we aim to shed light on a fascinating new aspect of cellular
communication involving extracellular vesicles (EVs) and their cargo of microRNAs (EV …

Predictive biomarkers for immune-related adverse events in cancer patients treated with immune-checkpoint inhibitors

J Wang, Y Ma, H Lin, J Wang, B Cao - BMC immunology, 2024 - Springer
Purpose The objective of this study was to identify potential predictors of immune-related
adverse events (irAEs) in cancer patients receiving immune checkpoint inhibitor therapy …

Assessing the global impact of ambient air pollution on cancer incidence and mortality: A comprehensive meta-analysis

T Ramamoorthy, A Nath, S Singh, S Mathew… - JCO Global …, 2024 - ascopubs.org
PURPOSE This study aims to examine the association between exposure to major ambient
air pollutants and the incidence and mortality of lung cancer and some nonlung cancers …

Mass spectrometry-detected MGUS is associated with obesity and other novel modifiable risk factors in a high-risk population

DJ Lee, H El-Khoury, AC Tramontano… - Blood …, 2024 - ashpublications.org
Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant condition
of multiple myeloma with few known risk factors. The emergence of mass spectrometry (MS) …

AST/ALT-to-platelet ratio (AARPRI) predicts gynaecological cancers: A 8-years follow-up study in 653 women

L Crudele, C De Matteis, G Graziano, F Novielli… - Scientific Reports, 2023 - nature.com
Non-alcoholic fatty liver disease (NAFLD), specifically liver steatosis and fibrosis with
steatohepatitis (NASH), is often associated with visceral adiposopathy, whose pathogenetic …