Frozen shoulder

NL Millar, A Meakins, F Struyf, E Willmore… - Nature reviews Disease …, 2022 - nature.com
Frozen shoulder is a common debilitating disorder characterized by shoulder pain and
progressive loss of shoulder movement. Frozen shoulder is frequently associated with other …

The epithelial–mesenchymal plasticity landscape: Principles of design and mechanisms of regulation

J Haerinck, S Goossens, G Berx - Nature Reviews Genetics, 2023 - nature.com
Epithelial–mesenchymal plasticity (EMP) enables cells to interconvert between several
states across the epithelial–mesenchymal landscape, thereby acquiring hybrid epithelial …

Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction

M Fan, K Yang, X Wang, L Chen, PS Gill, T Ha… - Science …, 2023 - science.org
High levels of lactate are positively associated with the prognosis and mortality in patients
with heart attack. Endothelial-to-mesenchymal transition (EndoMT) plays an important role in …

Endothelial to mesenchymal transition: role in physiology and in the pathogenesis of human diseases

S Piera-Velazquez, SA Jimenez - Physiological reviews, 2019 - journals.physiology.org
Numerous studies have demonstrated that endothelial cells are capable of undergoing
endothelial to mesenchymal transition (EndMT), a newly recognized type of cellular …

Endothelial to Mesenchymal Transition in Cardiovascular Disease: JACC State-of-the-Art Review

JC Kovacic, S Dimmeler, RP Harvey, T Finkel… - Journal of the American …, 2019 - jacc.org
Endothelial to mesenchymal transition (EndMT) is a process whereby an endothelial cell
undergoes a series of molecular events that lead to a change in phenotype toward a …

TGF‐β as a driver of fibrosis: physiological roles and therapeutic opportunities

EH Budi, JR Schaub, M Decaris, S Turner… - The Journal of …, 2021 - Wiley Online Library
Many chronic diseases are marked by fibrosis, which is defined by an abundance of
activated fibroblasts and excessive deposition of extracellular matrix, resulting in loss of …

[HTML][HTML] TGF-β-induced endothelial to mesenchymal transition in disease and tissue engineering

J Ma, G Sanchez-Duffhues, MJ Goumans… - Frontiers in cell and …, 2020 - frontiersin.org
Endothelial to mesenchymal transition (EndMT) is a complex biological process that gives
rise to cells with multipotent potential. EndMT is essential for the formation of the …

[HTML][HTML] Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulate regenerative wound healing via transforming growth factor-β receptor …

Y Zhang, Y Pan, Y Liu, X Li, L Tang, M Duan… - Stem cell research & …, 2021 - Springer
Background Scar formation is a common consequence of skin wound healing, and no
effective treatment exists. Umbilical cord blood mesenchymal stem cells (UCB-MSCs) can …

Endothelial-mesenchymal transition in cardiovascular disease

Z Alvandi, J Bischoff - Arteriosclerosis, thrombosis, and vascular …, 2021 - Am Heart Assoc
Endothelial-to-mesenchymal transition is a dynamic process in which endothelial cells
suppress constituent endothelial properties and take on mesenchymal cell behaviors. To …

[HTML][HTML] Through the layers: how macrophages drive atherosclerosis across the vessel wall

LI Susser, KJ Rayner - The Journal of clinical investigation, 2022 - Am Soc Clin Investig
Cardiovascular disease (CVD) accounts for almost half of all deaths related to non-
communicable disease worldwide, making it the single largest global cause of mortality …