Endothelial-tumor cell interaction in brain and CNS malignancies
M Peleli, A Moustakas, A Papapetropoulos - International journal of …, 2020 - mdpi.com
Glioblastoma and other brain or CNS malignancies (like neuroblastoma and
medulloblastoma) are difficult to treat and are characterized by excessive vascularization …
medulloblastoma) are difficult to treat and are characterized by excessive vascularization …
A dual role of YAP in driving TGFβ-mediated endothelial-to-mesenchymal transition
C Savorani, M Malinverno, R Seccia… - Journal of Cell …, 2021 - journals.biologists.com
Endothelial-to-mesenchymal transition (EndMT) is the biological process through which
endothelial cells transdifferentiate into mesenchymal cells. During embryo development …
endothelial cells transdifferentiate into mesenchymal cells. During embryo development …
The role of endothelial progenitors in the repair of vascular damage in systemic sclerosis
N Del Papa, F Pignataro - Frontiers in Immunology, 2018 - frontiersin.org
Systemic sclerosis (SSc) is a connective tissue disease characterized by a complex
pathological process where the main scenario is represented by progressive loss of …
pathological process where the main scenario is represented by progressive loss of …
Extracellular matrix roles in cardiorenal fibrosis: Potential therapeutic targets for CVD and CKD in the elderly
H Toba, ML Lindsey - Pharmacology & therapeutics, 2019 - Elsevier
Whereas hypertension, diabetes, and dyslipidemia are age-related risk factors for
cardiovascular disease (CVD) and chronic kidney disease (CKD), aging alone is an …
cardiovascular disease (CVD) and chronic kidney disease (CKD), aging alone is an …
Endothelial-specific loss of IFT88 promotes endothelial-to-mesenchymal transition and exacerbates bleomycin-induced pulmonary fibrosis
S Singh, M Adam, PN Matkar, A Bugyei-Twum… - Scientific Reports, 2020 - nature.com
Abstract Intraflagellar transport protein 88 (Ift88) is required for ciliogenesis and shear stress-
induced dissolution of cilia in embryonic endothelial cells coincides with endothelial-to …
induced dissolution of cilia in embryonic endothelial cells coincides with endothelial-to …
Oxidative storm induced by tryptophan metabolites: missing link between atherosclerosis and chronic kidney disease
I Kwiatkowska, JM Hermanowicz… - Oxidative Medicine …, 2020 - Wiley Online Library
Chronic kidney disease (CKD) occurrence is rising all over the world. Its presence is
associated with an increased risk of premature death from cardiovascular disease (CVD) …
associated with an increased risk of premature death from cardiovascular disease (CVD) …
Role of HIF‐1α in pathogenic mechanisms of keloids
Z Qiu, M Zhang, W Zhang, Z Li, L Si… - Journal of Cosmetic …, 2023 - Wiley Online Library
Abstract Backgrouds and Objective Keloids are defined as overrepairing products that
develop after skin lesions. Keloids are characterized by the proliferation of fibroblasts and …
develop after skin lesions. Keloids are characterized by the proliferation of fibroblasts and …
Perspectives of PDE inhibitor on treating idiopathic pulmonary fibrosis
X Yang, Z Xu, S Hu, J Shen - Frontiers in Pharmacology, 2023 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease (ILD)
without an identifiable cause. If not treated after diagnosis, the average life expectancy is 3 …
without an identifiable cause. If not treated after diagnosis, the average life expectancy is 3 …
TFPI2 suppresses the interaction of TGF-β2 pathway regulators to promote endothelial–mesenchymal transition in diabetic nephropathy
G Guan, J Xie, Y Dai, H Han - Journal of Biological Chemistry, 2022 - ASBMB
Endothelial–mesenchymal transition (EndMT) is an important source of myofibroblasts, but
also contributes to the progression of diabetic nephropathy (DN). By several differential …
also contributes to the progression of diabetic nephropathy (DN). By several differential …
Endothelial-to-mesenchymal transition in atherosclerosis: friend or foe?
S Gole, S Tkachenko, T Masannat, RA Baylis… - Cells, 2022 - mdpi.com
Despite many decades of research, complications of atherosclerosis resulting from the
rupture or erosion of unstable plaques remain the leading cause of death worldwide …
rupture or erosion of unstable plaques remain the leading cause of death worldwide …