Targeting Nrf2 to suppress ferroptosis and mitochondrial dysfunction in neurodegeneration
M Abdalkader, R Lampinen, KM Kanninen… - Frontiers in …, 2018 - frontiersin.org
Ferroptosis is a newly described form of regulated cell death, distinct from apoptosis,
necroptosis and other forms of cell death. Ferroptosis is induced by disruption of glutathione …
necroptosis and other forms of cell death. Ferroptosis is induced by disruption of glutathione …
[HTML][HTML] Iron mediated toxicity and programmed cell death: A review and a re-examination of existing paradigms
Iron is an essential micronutrient that is problematic for biological systems since it is toxic as
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …
Airborne, vehicle-derived Fe-bearing nanoparticles in the urban environment: a review
Airborne particulate matter poses a serious threat to human health. Exposure to nanosized
(< 0.1 μm), vehicle-derived particulates may be hazardous due to their bioreactivity, their …
(< 0.1 μm), vehicle-derived particulates may be hazardous due to their bioreactivity, their …
[HTML][HTML] The Nrf2 induction prevents ferroptosis in Friedreich's Ataxia
P La Rosa, S Petrillo, R Turchi, F Berardinelli… - Redox biology, 2021 - Elsevier
Ferroptosis is an iron-dependent cell death caused by impaired glutathione metabolism,
lipid peroxidation and mitochondrial failure. Emerging evidences report a role for ferroptosis …
lipid peroxidation and mitochondrial failure. Emerging evidences report a role for ferroptosis …
Oxidative stress and neurodegeneration: the involvement of iron
A Carocci, A Catalano, MS Sinicropi, G Genchi - Biometals, 2018 - Springer
Many evidences indicate that oxidative stress plays a significant role in a variety of human
disease states, including neurodegenerative diseases. Iron is an essential metal for almost …
disease states, including neurodegenerative diseases. Iron is an essential metal for almost …
Brain iron homeostasis: a focus on microglial iron
IC Nnah, M Wessling-Resnick - Pharmaceuticals, 2018 - mdpi.com
Iron is an essential trace element required for important brain functions including oxidative
metabolism, synaptic plasticity, myelination, and the synthesis of neurotransmitters …
metabolism, synaptic plasticity, myelination, and the synthesis of neurotransmitters …
Applications of surface‐enhanced Raman spectroscopy in environmental detection
As the human population grows, the anthropogenic impacts from various agricultural and
industrial processes produce unwanted contaminants in the environment. The accurate …
industrial processes produce unwanted contaminants in the environment. The accurate …
Dietary plant polyphenols as the potential drugs in neurodegenerative diseases: current evidence, advances, and opportunities
L Yan, MS Guo, Y Zhang, L Yu, JM Wu… - Oxidative Medicine …, 2022 - Wiley Online Library
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
and Huntington's disease (HD), are characterized by the progressive degeneration of …
and Huntington's disease (HD), are characterized by the progressive degeneration of …
Chemical tools for detecting Fe ions
T Hirayama, H Nagasawa - Journal of clinical biochemistry and …, 2017 - jstage.jst.go.jp
抄録 Owing to its distinctive electrochemical properties with interconvertible multiple
oxidation states, iron plays a significant role in various physiologically important functions …
oxidation states, iron plays a significant role in various physiologically important functions …
Identification of key structural features of the elusive Cu–Aβ complex that generates ROS in Alzheimer's disease
C Cheignon, M Jones, E Atrián-Blasco, I Kieffer… - Chemical …, 2017 - pubs.rsc.org
Oxidative stress is linked to the etiology of Alzheimer's disease (AD), the most common
cause of dementia in the elderly. Redox active metal ions such as copper catalyze the …
cause of dementia in the elderly. Redox active metal ions such as copper catalyze the …