Metastases, which are the leading cause of death in patients with cancer, have metabolic
vulnerabilities. Alterations in metabolism fuel the energy and biosynthetic needs of …

Endometriosis (EM) is one of the vanquished wonted causes of chronic pelvic sting in
women and is closely associated with infertility. The long-term, complex, systemic, and post …

Coactivator-associated arginine methyltransferase 1 (CARM1), a type I protein arginine
methyltransferase (PRMT), has been widely reported to catalyze arginine methylation of …

The THO complex (THOC) is ubiquitously involved in RNA modification and various THOC
proteins have been reported to regulate tumor development. However, the role of THOC3 in …

F-box/LRR-repeat protein 7 (FBXL7) was predicted as a differentially expressed E3 ubiquitin
ligase in non-small cell lung cancer (NSCLC), which has been suggested to influence …

Background ER+ breast cancer (ER+ BC) is the most common subtype of BC. Recently,
CDK4/6 inhibitors combined with aromatase inhibitors have been approved by FDA as the …

Background Belonging to the protein arginine methyltransferase (PRMT) family, the enzyme
encoded by coactivator associated arginine methyltransferase 1 (CARM1) catalyzes the …

Background NSCLC (non-small cell lung cancer) has become the malignancy with the
highest incidence and mortality rate worldwide. Fructose-6-phosphate 2-kinase/fructose-2, 6 …

Melanoma is a highly aggressive skin cancer and accounts for most of the skin cancer-
related deaths. The efficacy of current therapies for melanoma remains to be improved. The …

Fibroblast growth factors (FGFs) are expressed in both developing and adult tissues and
play important roles in embryogenesis, tissue homeostasis, angiogenesis, and neoplastic …