CD4+ T cells are central to the function of the immune system but their role in tumor
immunity remains underappreciated. It is becoming clear that there is an enormous diversity …

MHC class I antigens play a crucial role in the interaction of tumor cells with the host immune
system, in particular, in the presentation of peptides as tumor‐associated antigens to …

Abstract Purpose: A phase I/II study was conducted to investigate the safety, tolerability and
clinical response to vaccination with a combination of telomerase peptides GV1001 (hTERT …

Immunotherapies have shown considerable efficacy for the treatment of various cancers, but
a multitude of patients remain unresponsive for various reasons, including poor homing of T …

Therapy-resistant leukemia stem and progenitor cells (LSC) are a main cause of acute
myeloid leukemia (AML) relapse. LSC-targeting therapies may thus improve outcome of …

Oncolytic measles viruses (MV) derived from the live attenuated vaccine strain have been
engineered for increased antitumor activity, and are currently under investigation in clinical …

Methods: Based on a comprehensive search of the PubMed and ClinicalTrials. gov
database, this review included the literature reporting the immune escape mechanisms of …

Simple Summary Head and neck cancers are the sixth most common cancer in the world.
The burden of the disease has remained challenging over recent years despite the …

Cancer remains one of the leading causes of death worldwide, both in developed and in
developing nations. It may affect people at all ages, even fetuses, but the risk for most …

Chimeric antigen receptor (CAR) T cells provide a promising approach to the treatment of
hematologic malignancies and solid tumors. Flow cytometry is a powerful analytical …