Cryptococcal meningitis

L Tugume, K Ssebambulidde, J Kasibante… - Nature Reviews …, 2023 - nature.com
Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

The high osmolarity glycerol (HOG) pathway in fungi

H Yaakoub, NS Sanchez, L Ongay-Larios… - Critical Reviews in …, 2022 - Taylor & Francis
While fungi are widely occupying nature, many species are responsible for devastating
mycosis in humans. Such niche diversity explains how quick fungal adaptation is necessary …

[HTML][HTML] Importance of Clinical Isolates in Cryptococcus neoformans Research

KM Jackson, M Ding, K Nielsen - Journal of Fungi, 2023 - mdpi.com
The human pathogenic fungus Cryptococcus neoformans is a global health concern.
Previous research in the field has focused on studies using reference strains to identify …

[HTML][HTML] Catestatin: antimicrobial functions and potential therapeutics

S Jati, S Mahata, S Das, S Chatterjee, SK Mahata - Pharmaceutics, 2023 - mdpi.com
The rapid increase in drug-resistant and multidrug-resistant infections poses a serious
challenge to antimicrobial therapies, and has created a global health crisis. Since …

[HTML][HTML] Pulmonary cryptococcosis after recovery from COVID-19 in an immunocompetent patient: a rare case report

HS Choi - Medicine, 2022 - journals.lww.com
Written informed consent was obtained from the patient for the publication of this article and
any accompanying images. A copy of the written consent is available for review by the Editor …

[HTML][HTML] Vaccine protection by Cryptococcus neoformans Δsgl1 is mediated by γδ T cells via TLR2 signaling

TG Normile, TH Chu, BS Sheridan, M Del Poeta - Mucosal immunology, 2022 - Elsevier
We previously reported that administration of Cryptococcus neoformans Δsgl1 mutant
vaccine, accumulating sterylglucosides (SGs) and having normal capsule (GXM), protects …

[HTML][HTML] Cryptococcus neoformans adapts to the host environment through TOR-mediated remodeling of phospholipid asymmetry

LC Ristow, AJ Jezewski, BJ Chadwick… - Nature …, 2023 - nature.com
Cryptococcus spp. are environmental fungi that first must adapt to the host environment
before they can cause life-threatening meningitis in immunocompromised patients. Host …

[HTML][HTML] Identification of novel drug targets and screening potential drugs against Cryptococcus gattii: an in silico approach

TB Robin, NA Rani, N Ahmed, AA Prome… - Informatics in Medicine …, 2023 - Elsevier
Cryptococcus gattii is an emerging fungal pathogen responsible for causing cryptococcosis,
which is an infectious disease with a global prevalence and a wide range of clinical …

Cryptococcus spp. and Cryptococcosis: focusing on the infection in Brazil

FN do Carmo, J de Camargo Fenley, MT Garcia… - Brazilian Journal of …, 2022 - Springer
Cryptococcosis is a global fungal infection caused by the Cryptococcus neoformans/
Cryptococcus gattii yeast complex. This infection is acquired by inhalation of propagules …

Comparative miRNA transcriptomics of macaques and mice reveals MYOC is an inhibitor for Cryptococcus neoformans invasion into the brain

H Li, X Han, W Du, Y Meng, Y Li, T Sun… - Emerging Microbes & …, 2022 - Taylor & Francis
Cryptococcal meningoencephalitis (CM) is emerging as an infection in HIV/AIDS patients
shifted from primarily ARTnaive to ART-experienced individuals, as well as patients with …