With cardiovascular disease being the leading cause of morbidity and mortality worldwide,
effective and cost-efficient therapies to reduce cardiovascular risk are highly needed. Lipids …

Objective: The aim was to develop clinical practice guidelines on hypertriglyceridemia.
Participants: The Task Force included a chair selected by The Endocrine Society Clinical …

The metabolic syndrome (MetS) is comprised of a cluster of closely related risk factors,
including visceral adiposity, insulin resistance, hypertension, high triglyceride, and low high …

The ability of insulin to stimulate glucose uptake varies widely from person to person, and
these differences, as well as how the individual attempts to compensate for them, are of …

The metabolism of high-density lipoproteins (HDL), which are inversely related to risk of
atherosclerotic cardiovascular disease, involves a complex interplay of factors regulating …

BACKGROUND A growing body of evidence from epidemiological data, animal studies, and
clinical trials supports HDL as the next target to reduce residual cardiovascular risk in statin …

High-density lipoproteins comprise roughly 25–30% of the circulating proteins involved in
the transport of lipids in circulation. These particles differ in size and lipid composition …

Nicotinic acid has, like the Roman God Janus, two faces. One is the vitamin. The other is the
broad‐spectrum lipid drug. The Canadian pathologist Rudolf Altschul discovered 50 years …

Purpose of review Insulin resistance (IR) is recognized to play an important role in the
pathogenesis of dyslipidemia. This review summarizes the complex interplay between IR …

Values of insulin-mediated glucose disposal vary continuously throughout a population of
apparently healthy persons, and a difference of≥ 600% exists between the most insulin …