Quality of life in inflammatory bowel disease: a systematic review and meta-analyses—part II

SR Knowles, L Keefer, H Wilding… - Inflammatory bowel …, 2018 - academic.oup.com
Background There has been burgeoning interest in quality of life (QoL) in inflammatory
bowel disease (IBD) in recent decades, with hundreds of studies each year now assessing …

Current best practice for disease activity assessment in IBD

AJ Walsh, RV Bryant, SPL Travis - Nature reviews Gastroenterology & …, 2016 - nature.com
Therapeutic advances in the management of IBD have led to a paradigm shift in the
assessment of IBD disease activity. Beyond clinical remission, objective assessment of …

Effects of low FODMAP diet on symptoms, fecal microbiome, and markers of inflammation in patients with quiescent inflammatory bowel disease in a randomized trial

SR Cox, JO Lindsay, S Fromentin, AJ Stagg… - Gastroenterology, 2020 - Elsevier
Background & Aims There is limited evidence that a diet low in fermentable
oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) reduces gut …

The Warwick-Edinburgh mental well-being scale (WEMWBS): development and UK validation

R Tennant, L Hiller, R Fishwick, S Platt… - Health and Quality of life …, 2007 - Springer
Background There is increasing international interest in the concept of mental well-being
and its contribution to all aspects of human life. Demand for instruments to monitor mental …

A randomised, double-blind, placebo-controlled trial of a multi-strain probiotic in patients with asymptomatic ulcerative colitis and Crohn's disease

I Bjarnason, G Sission, BH Hayee - Inflammopharmacology, 2019 - Springer
Background There is considerable interest in the possible importance of the gut microflora in
the pathophysiology of the inflammatory bowel diseases (IBD) ulcerative colitis (UC) and …

Infliximab versus ciclosporin for steroid-resistant acute severe ulcerative colitis (CONSTRUCT): a mixed methods, open-label, pragmatic randomised trial

JG Williams, MF Alam, L Alrubaiy, I Arnott… - The lancet …, 2016 - thelancet.com
Background Infliximab and ciclosporin are of similar efficacy in treating acute severe
ulcerative colitis, but there has been no comparative evaluation of their relative clinical …

Patient-reported outcomes as primary end points in clinical trials of inflammatory bowel disease

N Williet, WJ Sandborn, L Peyrin–Biroulet - Clinical Gastroenterology and …, 2014 - Elsevier
The Food and Drug Administration (FDA) is moving from the Crohn's Disease Activity Index
to patient-reported outcomes (PROs) and objective measures of disease, such as findings …

Developing a standard set of patient-centred outcomes for inflammatory bowel disease—an international, cross-disciplinary consensus

AH Kim, C Roberts, BG Feagan… - Journal of Crohn's …, 2018 - academic.oup.com
Abstract Background and Aims Success in delivering value-based healthcare involves
measuring outcomes that matter most to patients. Our aim was to develop a minimum …

Development and validation of a rapid, generic measure of disease control from the patient's perspective: the IBD-control questionnaire

K Bodger, C Ormerod, D Shackcloth, M Harrison - Gut, 2014 - gut.bmj.com
Introduction The use of patient reported outcome measures to support routine inflammatory
bowel disease (IBD) care is not widespread and suggests that existing questionnaires lack …

Development and initial psychometric validation of a patient-reported outcome measure for Crohn's perianal fistula: the Crohn's Anal Fistula Quality of Life (CAF-QoL) …

SO Adegbola, L Dibley, K Sahnan, T Wade, A Verjee… - Gut, 2021 - gut.bmj.com
Introduction Crohn's perianal fistulas are challenging for patients and clinicians. Many do not
respond to available treatments and despite recommendations by a global consensus, there …