Role of oxidative stress, infection and inflammation in male infertility

A Agarwal, M Rana, E Qiu, H AlBunni, AD Bui… - Andrologia, 2018 - Wiley Online Library
Oxidative stress (OS), defined as an overabundance of reactive oxygen species (ROS) or a
deficiency of antioxidants, has been linked to sperm damage and male infertility. There are …

Causes and consequences of oxidative stress in spermatozoa

RJ Aitken, Z Gibb, MA Baker, J Drevet… - Reproduction, Fertility …, 2016 - CSIRO Publishing
Spermatozoa are highly vulnerable to oxidative attack because they lack significant
antioxidant protection due to the limited volume and restricted distribution of cytoplasmic …

[HTML][HTML] The role of oxidative stress and antioxidants in male fertility

R Walczak–Jedrzejowska, JK Wolski… - … European journal of …, 2013 - ncbi.nlm.nih.gov
Oxidative stress results from the imbalance between production of the reactive oxygen
species (ROS) and the protective effect of the antioxidant system responsible for their …

Reactive oxygen species and sperm cells

D Sanocka, M Kurpisz - Reproductive biology and endocrinology, 2004 - Springer
There is a dynamic interplay between pro-and anti-oxidant substances in human ejaculate.
Excessive reactive oxygen species (ROS) generation can overwhelm protective mechanism …

A search for molecular mechanisms underlying male idiopathic infertility

A Bracke, K Peeters, U Punjabi, D Hoogewijs… - Reproductive …, 2018 - Elsevier
Infertility affects approximately 15% of the couples wanting to conceive. In 30− 40% of the
cases the aetiology of male infertility remains unknown and is called idiopathic male …

Infections in the male genital tract and reactive oxygen species

FR Ochsendorf - Human Reproduction Update, 1999 - academic.oup.com
In the male genital tract, reactive oxygen species (ROS) are generated by spermatozoa and
leukocytes including neutrophils and macrophages. ROS are involved in the regulation of …

[HTML][HTML] Withania somnifera improves semen quality by regulating reproductive hormone levels and oxidative stress in seminal plasma of infertile males

MK Ahmad, AA Mahdi, KK Shukla, N Islam… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To investigate the impact of Withania somnifera roots on semen profile,
oxidative biomarkers, and reproductive hormone levels of infertile men. DESIGN …

The effects of cigarette smoking on male fertility

JR Kovac, A Khanna, LI Lipshultz - Postgraduate medicine, 2015 - Taylor & Francis
Cigarette smoking, one of the main causes of preventable morbidity and mortality, has a
multitude of well-known side effects. The relationship between cigarette smoking and …

Reproductive toxicity of metals in men

A Pizent, B Tariba, T Živković - Arhiv za higijenu rada i toksikologiju, 2012 - hrcak.srce.hr
Sažetak A combination of genetic, environmental and lifestyle factors contributes to adverse
effects on the reproductive health in men. Metals are pervasive in food, water, air, tobacco …

Antioxidants and sperm DNA damage: a clinical perspective

A Zini, M San Gabriel, A Baazeem - Journal of assisted reproduction and …, 2009 - Springer
Purpose Infertile men possess substantially more sperm DNA damage than do fertile men,
damage that may impact negatively on reproductive outcomes. In this era of assisted …