Predicting long-term cognitive and neuropathological consequences of moderate to severe traumatic brain injury: Review and theoretical framework
Prognostic modeling in moderate to severe traumatic brain injury (TBI) has historically
focused primarily on the projection of crude outcomes such as the risk of mortality and …
focused primarily on the projection of crude outcomes such as the risk of mortality and …
Age at first exposure to repetitive head impacts is associated with smaller thalamic volumes in former professional American football players
Thalamic atrophy has been associated with exposure to repetitive head impacts (RHI) in
professional fighters. The aim of this study is to investigate whether or not age at first …
professional fighters. The aim of this study is to investigate whether or not age at first …
Lumbar cerebrospinal fluid-to-brain extracellular fluid surrogacy is context-specific: insights from LeiCNS-PK3. 0 simulations
MAA Saleh, CF Loo, J Elassaiss-Schaap… - … of Pharmacokinetics and …, 2021 - Springer
Predicting brain pharmacokinetics is critical for central nervous system (CNS) drug
development yet difficult due to ethical restrictions of human brain sampling. CNS …
development yet difficult due to ethical restrictions of human brain sampling. CNS …
Executive functions, self-awareness and quality of life in chronic moderate-to-severe TBI
E Pettemeridou, MRT Kennedy… - …, 2020 - content.iospress.com
BACKGROUND: Moderate-to-severe traumatic brain injury (TBI) leads to significant
neuropsychological impairment, further affecting quality of life (QOL). OBJECTIVE …
neuropsychological impairment, further affecting quality of life (QOL). OBJECTIVE …
Regional brain volume, brain reserve and MMSE performance in healthy aging from the NEUROAGE Cohort: Contributions of sex, education, and depression …
E Pettemeridou, E Kallousia… - Frontiers in Aging …, 2021 - frontiersin.org
Objective: The aim of this study was twofold. First, to investigate the relationship between
age, gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) volumes, brain …
age, gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) volumes, brain …
Altered resting functional connectivity is related to cognitive outcome in males with moderate-severe traumatic brain injury
TBI results in significant cognitive impairments and in altered brain functional connectivity.
However, no studies explored so far, the relationship between global functional connectivity …
However, no studies explored so far, the relationship between global functional connectivity …
Progressive neurodegeneration across chronic stages of severe traumatic brain injury
Objective: To examine the trajectory of structural gray matter changes across 2 chronic
periods of recovery in individuals who have sustained severe traumatic brain injury (TBI) …
periods of recovery in individuals who have sustained severe traumatic brain injury (TBI) …
Global hippocampal and selective thalamic nuclei atrophy differentiate chronic TBI from Non-TBI
J Sandry, E Dobryakova - Cortex, 2021 - Elsevier
Traumatic brain injury (TBI) may increase susceptibility to neurodegenerative diseases later
in life. One neurobiological parallel between chronic TBI and neurodegeneration may be …
in life. One neurobiological parallel between chronic TBI and neurodegeneration may be …
Altered grey matter structural covariance in chronic moderate–severe traumatic brain injury
Traumatic brain injury (TBI) alters brain network connectivity. Structural covariance networks
(SCNs) reflect morphological covariation between brain regions. SCNs may elucidate how …
(SCNs) reflect morphological covariation between brain regions. SCNs may elucidate how …
Fronto‐temporal vulnerability to disconnection in paediatric moderate and severe traumatic brain injury
E Molteni, E Pagani, S Strazzer… - European journal of …, 2019 - Wiley Online Library
Background In patients with moderate and severe paediatric traumatic brain injury (TBI), we
investigated the presence and severity of white matter (WM) tract damage, cortical lobar and …
investigated the presence and severity of white matter (WM) tract damage, cortical lobar and …