Transition metal elements, such as copper, play diverse and pivotal roles in oncology. They
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …

Benefiting from low costs, structural diversities, tunable catalytic activities, feasible
modifications, and high stability compared to the natural enzymes, reactive oxygen …

Despite metal‐based photosensitizers showing great potential in photodynamic therapy for
tumor treatment, the application of the photosensitizers is intrinsically limited by their poor …

In the past decade, the metallacycles/metallacages have attracted unremitting interest in
biomedical fields, yet visual tracking of their in vivo delivery, targeting ability, biodistribution …

Unsatisfied tumor accumulation of chemotherapeutic drugs and a complicated
immunosuppressive microenvironment diminish the immune response rate and the …

Ferroptosis is a form of programmed cell death driven by iron‐dependent lipid peroxidation
(LPO) with the potential for antitumor immunity activation. In this study, a nonferrous …

A second-generation series of biscyclometalated 2-(5-aryl-thienyl)-benzimidazole and-
benzothiazole Ir (III) dppz complexes [Ir (C^ N) 2 (dppz)]+, Ir1–Ir4, were rationally designed …

To develop next-generation metal drugs with high efficiency and low toxicity for targeting
inhibition of gastric tumor growth and metastasis, we not only optimized a series of …

Though immunogenic cell death (ICD) has garnered significant attention in the realm of
anticancer therapies, effectively stimulating strong immune responses with minimal side …

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon (STING) pathway is a key
mediator of innate immunity involved in cancer development and treatment. The roles of …