Psoriasis: which therapy for which patient: focus on special populations and chronic infections

SB Kaushik, MG Lebwohl - Journal of the American Academy of …, 2019 - Elsevier
Despite the availability of several new systemic agents for psoriasis treatment, choosing the
right therapy in certain patient populations can be challenging. There are few up-to-date …

Non-specificity as the sticky problem in therapeutic antibody development

H Ausserwöger, MM Schneider, TW Herling… - Nature Reviews …, 2022 - nature.com
Antibodies are highly potent therapeutic scaffolds with more than a hundred different
products approved on the market. Successful development of antibody-based drugs …

Placental transfer of anti–tumor necrosis factor agents in pregnant patients with inflammatory bowel disease

U Mahadevan, DC Wolf, M Dubinsky, A Cortot… - Clinical …, 2013 - Elsevier
BACKGROUND & AIMS: Some women with inflammatory bowel disease require therapy
with tumor necrosis factor (TNF) antagonists during pregnancy. It is not clear whether these …

The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Special situations

G Van Assche, A Dignass, W Reinisch… - Journal of Crohn's …, 2010 - academic.oup.com
Fistulating Crohn's disease (CD) comprises fistulae arising in the perianal area, together
with those communicating between the intestine and other organs or the abdominal wall …

British Association of Dermatologists' guidelines for biologic interventions for psoriasis 2009

CH Smith, AV Anstey, J Barker… - British Journal of …, 2009 - academic.oup.com
1.0 Background Psoriasis is a common, chronic inflammatory skin disease which typically
follows a relapsing and remitting course, and is associated with joint disease in …

An interspecies comparison of placental antibody transfer: new insights into developmental toxicity testing of monoclonal antibodies

N Pentšuk, JW van der Laan - Birth Defects Research Part B …, 2009 - Wiley Online Library
There are profound differences in maternofetal transfer of immunoglobulins between
species with extensive gestational transfer of maternal immunoglobulins in primates …

Placental transport of immunoglobulins: a clinical review for gastroenterologists who prescribe therapeutic monoclonal antibodies to women during conception and …

SV Kane, LA Acquah - Official journal of the American College of …, 2009 - journals.lww.com
The introduction of biologic therapy with therapeutic monoclonal antibodies to the treatment
strategies of inflammatory bowel disease (IBD) has significantly changed the way clinicians …

The London position statement of the world Congress of gastroenterology on biological therapy for IBD with the European Crohn's and colitis organisation: pregnancy …

U Mahadevan, S Cucchiara, JS Hyams… - Official journal of the …, 2011 - journals.lww.com
Women with inflammatory bowel disease (IBD) have similar rates of fertility to the general
population, but have an increased rate of adverse pregnancy outcomes compared with the …

Research gaps in psoriasis: opportunities for future studies

C Ryan, NJ Korman, JM Gelfand, HW Lim… - Journal of the American …, 2014 - Elsevier
Over the past 2 decades, considerable progress has been made to further elucidate the
complex pathogenesis of psoriasis, facilitating the development of a new armamentarium of …

European evidenced-based consensus on reproduction in inflammatory bowel disease

CJ van der Woude, S Kolacek, I Dotan… - Journal of Crohn's …, 2010 - academic.oup.com
Inflammatory bowel diseases (IBD) typically affect patients in their reproductive years. It has
been shown that reproductive issues are of key concern to IBD patients, 1 especially …