Pancreatic cancer is a devastating disease with very poor prognosis. Currently, surgery
followed by adjuvant chemotherapy represents the only curative option which, unfortunately …

Simple Summary Pancreatic ductal adenocarcinoma is a devastating disease that is very
hard to treat. Here, we advance and evaluate the notion that the best possible management …

Macropinocytosis has emerged as an important nutrient-scavenging pathway that supports
tumor cell fitness. By internalizing extracellular protein and targeting it for lysosomal …

Objective To investigate the role of lncRNA-BLACAT1 in promoting H3K27 trimethylation of
CDKN1C gene by recruiting EZH2 to regulate CCNE on glycolysis and mitochondrial …

Context Pancreatic cancer (PDAC) is one of the most challenging cancers to treat with
modest recent improvements in survival from new systemic therapies. There is growing …

This review highlights current treatments, limitations, and pitfalls in the management of
pancreatic cancer and discusses current research in novel targets and drug development to …

The relationship between treatment outcome and cutaneous toxicity induced by anticancer
therapy has gained attention in the past decade. In this article, we have provided an …

Background: While liposomal cisplatin has shown enhanced drug tolerability and higher
targeting property as compared with the conventional cisplatin, the doubt remains whether …

Objectives Chemotheraputic drug resistance is a critical factor associated with the poor
survival in advanced/metastatic pancreatic cancer (PC) patients. Methods Human pancreatic …

Pancreatic ductal adenocarcinoma (PDAC), a prominent cause of cancer deaths worldwide,
is a highly aggressive cancer most frequently detected at an advanced stage that limits …