[HTML][HTML] Pederins, mycalamides, onnamides and theopederins: Distinctive polyketide families with intriguing therapeutic potentialities

MA Tammam, A El-Demerdash - Current Research in Biotechnology, 2023 - Elsevier
In this comprehensive review article, an in-depth exploration over the period from 1949 to
2023 is presented, focusing on the discovery, chemistry, biosynthesis and therapeutic …

Catecholamine Derivatives: Natural Occurrence, Structural Diversity, and Biological Activity

KJ Tang, Y Zhao, X Tao, J Li, Y Chen… - Journal of Natural …, 2023 - ACS Publications
Catecholamines (CAs) are aromatic amines containing a 3, 4-dihydroxyphenyl nucleus and
an amine side chain. Representative CAs included the endogenous neurotransmitters …

[HTML][HTML] Investigating the hepatoprotective potentiality of marine-derived steroids as promising inhibitors of liver fibrosis

MA Tammam, F Pereira, O Aly, M Sebak, YM Diab… - RSC …, 2023 - pubs.rsc.org
It has been reported that organic extracts derived from soft corals belonging to the genus
Sarcophyton have exhibited a wide range of therapeutic characteristics. Based on …

Spectroscopic investigations, quantum chemical, molecular docking and drug likeness studies of t-butyl-3, 4, 5-trimethyl-2-pyrrole carboxylate

AK Bharathi, SC Jeyaseelan, S Hussain… - Journal of Molecular …, 2024 - Elsevier
The geometrical structure of t‑butyl‑3, 4, 5-trimethyl-2-pyrrole carboxylate (TBTPC) was
computed by DFT calculations using the B3LYP method and the 6–311++ G (d, p) basis set …

Progress on synthesis and structure-activity relationships of lamellarins over the past decade

M Wei, J Chen, Y Song, JP Monserrat, Y Zhang… - European Journal of …, 2024 - Elsevier
Lamellarins are polyaromatic alkaloids isolated from marine organisms, including mollusks,
tunicates, and sponges. Currently, over 100 structurally distinct natural lamellarins have …

[PDF][PDF] Current Research in Biotechnology

MA Tammam, O Aly, F Pereira, A Mahdy… - Current Research in …, 2024 - researchgate.net
Metabolic syndrome (MS) represents a global health challenge characterized by various
metabolic disorders, including HOMA-IR (insulin resistance), obesity, dyslipidemia, and …

Investigating the Structure-Activity Relationship of Laulimalides Marine Macrolides as Promising Inhibitors for SARS-CoV-2 Main Protease (Mpro)

AM Elgohary, AA Elfiky, F Pereira, MIG El-Din… - 2023 - chemrxiv.org
SARS-CoV-2, the new coronavirus variant is a world-wide health crisis. Over spans of
human history, preparations derived from natural products have always been recognized as …