Host genetic factors determining COVID-19 susceptibility and severity

TP Velavan, SR Pallerla, J Rüter, Y Augustin… - …, 2021 - thelancet.com
The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections …

Mesenchymal stem cell-based treatments for COVID-19: status and future perspectives for clinical applications

L Chen, J Qu, FS Kalyani, Q Zhang, L Fan… - Cellular and Molecular …, 2022 - Springer
As a result of cross-species transmission in December 2019, the coronavirus disease 2019
(COVID-19) became a serious endangerment to human health and the causal agent of a …

Glucose metabolism disorder: a potential accomplice of SARS-CoV-2

Y Luan, Y Luan, H He, B Jue, Y Yang, B Qin… - International Journal of …, 2023 - nature.com
Abstract Globally, 265,713,467 confirmed cases of SARS-CoV-2 (CoV-2), including
5,260,888 deaths, have been reported by the WHO. It is important to study the mechanism of …

[HTML][HTML] A retrospective analysis of COVID-19 mRNA vaccine breakthrough infections–risk factors and vaccine effectiveness

C Liu, J Lee, C Ta, A Soroush, JR Rogers, JH Kim… - Medrxiv, 2021 - ncbi.nlm.nih.gov
A Retrospective Analysis of COVID-19 mRNA Vaccine Breakthrough Infections – Risk
Factors and Vaccine Effectiveness - PMC Back to Top Skip to main content NIH NLM Logo …

[HTML][HTML] Risk factors associated with SARS-CoV-2 breakthrough infections in fully mRNA-vaccinated individuals: Retrospective analysis

C Liu, J Lee, C Ta, A Soroush… - JMIR Public Health …, 2022 - publichealth.jmir.org
Background COVID-19 messenger RNA (mRNA) vaccines have demonstrated efficacy and
effectiveness in preventing symptomatic COVID-19, while being relatively safe in trial …

Critical role of nitric oxide in impeding COVID-19 transmission and prevention: a promising possibility

R Rajendran, A Chathambath, AG Al-Sehemi… - … Science and Pollution …, 2022 - Springer
COVID-19 is a serious respiratory infection caused by a beta-coronavirus that is closely
linked to SARS. Hypoxemia is a symptom of infection, which is accompanied by acute …

UBR5 acts as an antiviral host factor against MERS-CoV via promoting ubiquitination and degradation of ORF4b

Y Zhou, R Zheng, D Liu, S Liu, C Disoma, S Li… - Journal of …, 2022 - Am Soc Microbiol
Within the past 2 decades, three highly pathogenic human coronaviruses have emerged,
namely, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East …

Prerequisite for COVID-19 prediction: a review on factors affecting the infection rate

SGH Tang, MHH Hadi, SR Arsad, PJ Ker… - International Journal of …, 2022 - mdpi.com
Since the year 2020, coronavirus disease 2019 (COVID-19) has emerged as the dominant
topic of discussion in the public and research domains. Intensive research has been carried …

Understanding the host-pathogen evolutionary balance through Gaussian process modeling of SARS-CoV-2

S Loguercio, BC Calverley, C Wang, D Shak, P Zhao… - Patterns, 2023 - cell.com
We have developed a machine learning (ML) approach using Gaussian process (GP)-based
spatial covariance (SCV) to track the impact of spatial-temporal mutational events driving …

Anti-interferon autoantibodies in adult-onset immunodeficiency syndrome and severe COVID-19 infection

LF Chen, CD Yang, XB Cheng - Frontiers in immunology, 2021 - frontiersin.org
Adult-onset immunodeficiency syndrome due to anti-interferon (IFN)-γ autoantibodies has
attracted much attention in recent years. It usually occurs in previously healthy people and …