Nrf2 and notch signaling in lung cancer: near the crossroad
A Sparaneo, FP Fabrizio… - Oxidative Medicine and …, 2016 - Wiley Online Library
The transcription factor Nrf2 (NF‐E2 related factor 2) is a master regulator of the cell
antioxidant response associated with tumor growth and resistance to cytotoxic treatments. In …
antioxidant response associated with tumor growth and resistance to cytotoxic treatments. In …
TGFβ receptor inhibitor galunisertib is linked to inflammation-and remodeling-related proteins in patients with pancreatic cancer
D Melisi, R Garcia-Carbonero, T Macarulla… - Cancer chemotherapy …, 2019 - Springer
Purpose Galunisertib, the first small molecule transforming growth factor beta (TGFβ)
receptor inhibitor, plus gemcitabine resulted in the improvement of survival in patients with …
receptor inhibitor, plus gemcitabine resulted in the improvement of survival in patients with …
The emergence of TRP channels interactome as a potential therapeutic target in pancreatic ductal adenocarcinoma
Integral membrane proteins, known as Transient Receptor Potential (TRP) channels, are
cellular sensors for various physical and chemical stimuli in the nervous system, respiratory …
cellular sensors for various physical and chemical stimuli in the nervous system, respiratory …
Chrysin-induced G protein-coupled estrogen receptor activation suppresses pancreatic cancer
HK Lim, HJ Kwon, GS Lee, JH Moon… - International Journal of …, 2022 - mdpi.com
Pancreatic cancer (PC) has a high mortality rate due to its poor prognosis and the possibility
of surgical resection in patients with the disease. Importantly, adjuvant chemotherapy is …
of surgical resection in patients with the disease. Importantly, adjuvant chemotherapy is …
Higher notch expression implies poor survival in pancreatic ductal adenocarcinoma: A systematic review and meta-analysis
J Ye, J Wen, Y Ning, Y Li - Pancreatology, 2018 - Elsevier
Background At present, pancreatic ductal adenocarcinoma (PDAC) is a fetal disease lack of
effective prognostic and therapeutic methods resulting in high mortality. The Notch signaling …
effective prognostic and therapeutic methods resulting in high mortality. The Notch signaling …
Notch4 inhibition reduces migration and invasion and enhances sensitivity to docetaxel by inhibiting Akt/fascin in pancreatic cancer cells
CJ Qian, YY Chen, X Zhang, FQ Liu… - Oncology …, 2016 - spandidos-publications.com
Overexpression of Notch4 is associated with a variety of tumor types. Only sparse
information exists on Notch4 expression in pancreatic cancer (PC). The present study …
information exists on Notch4 expression in pancreatic cancer (PC). The present study …
An Integrin-αvβ6/α5β1-Bitargeted Probe for the SPECT Imaging of Pancreatic Adenocarcinoma in Preclinical and Primary Clinical Studies
H Zhao, H Gao, C Luo, G Yang, X Zhao… - Bioconjugate …, 2021 - ACS Publications
Pancreatic adenocarcinoma (PA) is one of the deadliest human malignancies. However,
early detection, prediction of surgical resectability, and prognosis of PA are challenging with …
early detection, prediction of surgical resectability, and prognosis of PA are challenging with …
The FSHR expression in head and neck squamous cell cancer. a pilot immunohistochemical study
T Olejar, D Vetvicka, J Boucek, M Zabrodsky… - Anticancer …, 2020 - ar.iiarjournals.org
Background/Aim: Follicle-stimulating hormone receptor (FSHr), expressed on endothelial
cells of vessels in different malignant tumors, has been recently investigated as a potential …
cells of vessels in different malignant tumors, has been recently investigated as a potential …
Tocotrienol-rich mixture inhibits cell proliferation and induces apoptosis via down-regulation of the Notch-1/NF-κB pathways in NSCLC cells
LD Rajasinghe, SV Gupta - Nutrition and Dietary Supplements, 2017 - Taylor & Francis
Lung cancer is one of the leading causes of cancer deaths. Non-small cell lung cancer
(NSCLC), with a 5-year survival rate of 5% at stage IIIB, accounts for 80%–85% of all lung …
(NSCLC), with a 5-year survival rate of 5% at stage IIIB, accounts for 80%–85% of all lung …
Targeting the Endocannabinoid System: From the Need for New Therapies to the Development of a Promising Strategy. What About Pancreatic Cancer?
N Garmpis, C Damaskos, D Dimitroulis, A Garmpi… - in vivo, 2022 - iv.iiarjournals.org
Pancreatic cancer is one of the most fatal malignancies, and therefore, new strategies, which
aim at the improvement of the prognosis of this lethal disease, are needed. Many clinical …
aim at the improvement of the prognosis of this lethal disease, are needed. Many clinical …