[HTML][HTML] Gut liver brain axis in diseases: the implications for therapeutic interventions

M Yan, S Man, B Sun, L Ma, L Guo, L Huang… - Signal Transduction and …, 2023 - nature.com
Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …

[HTML][HTML] The gut microbial metabolite trimethylamine N-oxide and cardiovascular diseases

J Zhen, Z Zhou, M He, HX Han, EH Lv… - Frontiers in …, 2023 - frontiersin.org
Morbidity and mortality of cardiovascular diseases (CVDs) are exceedingly high worldwide.
Researchers have found that the occurrence and development of CVDs are closely related …

[HTML][HTML] Plasma markers of disrupted gut permeability in severe COVID-19 patients

LB Giron, H Dweep, X Yin, H Wang, M Damra… - Frontiers in …, 2021 - frontiersin.org
A disruption of the crosstalk between the gut and the lung has been implicated as a driver of
severity during respiratory-related diseases. Lung injury causes systemic inflammation …

[HTML][HTML] Gut microbiota metabolites in major depressive disorder—Deep insights into their pathophysiological role and potential translational applications

MA Ortega, MA Alvarez-Mon, C García-Montero… - Metabolites, 2022 - mdpi.com
The gut microbiota is a complex and dynamic ecosystem essential for the proper functioning
of the organism, affecting the health and disease status of the individuals. There is …

Can diet modulate trimethylamine N-oxide (TMAO) production? What do we know so far?

KS Coutinho-Wolino, LFM de F. Cardozo… - European journal of …, 2021 - Springer
Abstract Background Trimethylamine N-oxide (TMAO) is a metabolite that has attracted
attention due to its positive association with several chronic non-communicable diseases …

Non-alcoholic fatty liver disease and gut microbial dysbiosis-underlying mechanisms and gut microbiota mediated treatment strategies

M Jayachandran, S Qu - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
Non-alcoholic fatty liver disease (NAFLD) is by far the most prevalent form of liver disease
worldwide. It's also the leading cause of liver-related hospitalizations and deaths …

[HTML][HTML] Diet quality, gut microbiota, and microRNAs associated with mild cognitive impairment in middle-aged and elderly Chinese population

X Zhang, Y Wang, W Liu, T Wang, L Wang… - The American journal of …, 2021 - Elsevier
Background Diet, the gut microbiota, and microRNAs (miRNAs) have been recognized as
factors possibly influencing the pathogenesis of Alzheimer's disease. However, the …

Gut-brain axis a key player to control gut Dysbiosis in neurological diseases

I Pan, PK Issac, MM Rahman, A Guru… - Molecular …, 2023 - Springer
Parkinson's disease is a chronic neuropathy characterised by the formation of Lewy bodies
(misfolded alpha-synuclein) in dopaminergic neurons of the substantia nigra and other parts …

[HTML][HTML] Gut–Liver axis and non-alcoholic fatty liver disease: A vicious circle of dysfunctions orchestrated by the gut microbiome

S Pezzino, M Sofia, G Faletra, C Mazzone, G Litrico… - Biology, 2022 - mdpi.com
Simple Summary Non-alcoholic fatty liver disease (NAFLD) is a widespread disease
associated with metabolic disorders, such as obesity. In recent years, there has been …

[HTML][HTML] NAFLD and cardiovascular diseases: epidemiological, mechanistic and therapeutic considerations

D Niederseer, B Wernly, E Aigner, F Stickel… - Journal of Clinical …, 2021 - mdpi.com
Overwhelming evidence suggests an association of cardiovascular disease (CVD) with non-
alcoholic fatty liver disease (NAFLD); however, the underlying mechanisms remain largely …