[HTML][HTML] O sistema endocanabinoide e as dores orofaciais: atualidades e perspectivas

JPC Tanganeli, DS Haddad, SM Rode, CH Tambeli… - BrJP, 2023 - SciELO Brasil
RESUMO JUSTIFICATIVA E OBJETIVOS: Desde a descoberta relativamente recente do
sistema endocanabinoide (SEC) e seu papel fundamental da regulação de outros sistemas …

[HTML][HTML] The endocannabinoid system and orofacial pains: updates and perspectives

JPC Tanganeli, DS Haddad, SM Rode, CH Tambeli… - BrJP, 2023 - SciELO Brasil
ABSTRACT BACKGROUND AND OBJECTIVES: Since the relatively recent discovery of the
endocannabinoid system (ECS) and its fundamental role in regulating other systems, the …

[HTML][HTML] Injectable thermosensitive hydrogel loading erythropoietin and FK506 alleviates gingival inflammation and promotes periodontal tissue regeneration

Z Gu, C Qiu, L Chen, X Wang - Frontiers in Bioengineering and …, 2024 - frontiersin.org
Background: Periodontitis is a chronic multifactorial inflammatory disease associated with
dysbiotic plaque biofilms and characterized by progressive destruction of the tooth …

Phytocannabinoids and gingival inflammation: Preclinical findings and a placebo‐controlled double‐blind randomized clinical trial with cannabidiol

P Jirasek, A Jusku, J Frankova… - Journal of …, 2024 - Wiley Online Library
Objective The aim of this study was to:(1) evaluate the anti‐inflammatory effects of
cannabidiol (CBD) on primary cultures of human gingival fibroblasts (HGFs) and (2) to …

[HTML][HTML] Modulation of Redox and Inflammatory Signaling in Human Skin Cells Using Phytocannabinoids Applied after UVA Irradiation: In Vitro Studies

A Wroński, I Jarocka-Karpowicz, A Surażyński… - Cells, 2024 - mdpi.com
UVA exposure disturbs the metabolism of skin cells, often inducing oxidative stress and
inflammation. Therefore, there is a need for bioactive compounds that limit such …

[HTML][HTML] The Role of Different Types of Cannabinoids in Periodontal Disease: An Integrative Review

JC Monteiro Viana, GE da Silva Gomes… - Pharmaceutics, 2024 - mdpi.com
This integrative review addresses the potential of the Endocannabinoid System (ES) and
cannabinoids in the pathogenesis and treatment of periodontal disease (PD). Cannabinoid …

[HTML][HTML] Chemopreventive and Biological Strategies in the Management of Oral Potentially Malignant and Malignant Disorders

G Viglianisi, A Polizzi, C Grippaudo, S Cocuzza… - Bioengineering, 2024 - mdpi.com
Oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC)
represent a significant global health burden due to their potential for malignant …

[HTML][HTML] Endocannabinoid system and periodontitis: mechanisms and therapeutic implications

LFF Soares, LV Faria, JA Cirelli - Revista de Odontologia da UNESP, 2023 - SciELO Brasil
Introduction Periodontitis is a major public health problem. Although the principle of
periodontitis therapy is mainly focused on removing dental biofilm and associated factors, its …

Cellular experimental study and mechanism of surface modification of 3D printed titanium materials to modulate the sealing and antimicrobial properties of oral …

S Huang, F Guo, N Liu, K Hu… - European Journal of …, 2024 - journals.sagepub.com
Investigating the role of surface-modified 3D printed titanium implants in modulating oral soft
tissue closure and antimicrobial properties. Eighteen 6-month-old healthy adult New …

Thiolutin Reverses Lipopolysaccharide/Adenosine Triphosphate-Induced Pyroptosis and Inflammation in Human Gingival Fibroblasts by Suppressing NLRP3 …

Y Zheng, S Jiang - Journal of Hard Tissue Biology, 2023 - jstage.jst.go.jp
Pharmacological studies revealed that thiolutin (THL) prevented or treated NLRP3-
associated inflammatory diseases. The activation of the NLRP3 inflammasome plays a …