Glucocorticoids are effective immunomodulatory drugs used for many inflammatory
disorders as well as in transplant recipients. However, both iatrogenic and endogenous …

The increasingly female face of chronic obstructive pulmonary disease (COPD) prevalence
among women has equalled that of men since 2008, due in part to increased tobacco use …

Background Many patients with severe asthma require maintenance treatment with systemic
corticosteroids (SCSs) to control daily symptoms and prevent serious acute exacerbations …

Background Osteoporosis is common in patients with COPD, but its prevalence and
progression are not well characterized. Concerns have been raised over the possible …

Introduction The aim was to analyse data on the use of biochemical bone turnover markers
(BTM) in postmenopausal osteoporosis. Methods We carried out a comparative analysis of …

Oral glucocorticoids (GCs) are frequently used in the treatment of inflammatory conditions,
such as rheumatoid arthritis or asthma. They have adverse skeletal effects, primarily through …

Objectives: To provide an updated document assessing the global, NSAID-specific, and time
dependent risk of gastrointestinal (GI) complications through meta-analyses of high quality …

Glucocorticoids are widely used to treat several diseases; however, one of their major
consequences is a deleterious effect on bone that may lead to glucocorticoid-induced …

Osteoporosis is a global threat because it can impact every human being as they age. In this
new edition, the authors point out the enormous scale of the problem in terms of human …

Vitamin D metabolites alphacalcidol and calcitriol (D-hormones) have been investigated for
two decades, but few and conflicting results are available from high-quality randomized …