Gonorrhoea
M Unemo, HS Seifert, EW Hook III, S Hawkes… - Nature Reviews …, 2019 - nature.com
The bacterium Neisseria gonorrhoeae causes the sexually transmitted infection (STI)
gonorrhoea, which has an estimated global annual incidence of 86.9 million adults …
gonorrhoea, which has an estimated global annual incidence of 86.9 million adults …
Neisseria gonorrhoeae: Drug Resistance, Mouse Models, and Vaccine Development
PA Rice, WM Shafer, S Ram… - Annual review of …, 2017 - annualreviews.org
Gonorrhea, an obligate human infection, is on the rise worldwide and gonococcal strains
resistant to many antibiotics are emerging. Appropriate antimicrobial treatment and …
resistant to many antibiotics are emerging. Appropriate antimicrobial treatment and …
[HTML][HTML] Gonorrhea-an evolving disease of the new millennium
SA Hill, TL Masters, J Wachter - Microbial cell, 2016 - ncbi.nlm.nih.gov
Etiology, transmission and protection: Neisseria gonorrhoeae (the gonococcus) is the
etiological agent for the strictly human sexually transmitted disease gonorrhea. Infections …
etiological agent for the strictly human sexually transmitted disease gonorrhea. Infections …
Pathogenesis of Neisseria gonorrhoeae and the Host Defense in Ascending Infections of Human Fallopian Tube
JD Lenz, JP Dillard - Frontiers in immunology, 2018 - frontiersin.org
Neisseria gonorrhoeae is an obligate human pathogen that causes mucosal surface
infections of male and female reproductive tracts, pharynx, rectum, and conjunctiva …
infections of male and female reproductive tracts, pharynx, rectum, and conjunctiva …
Progress toward a gonococcal vaccine: the way forward
MW Russell, AE Jerse, SD Gray-Owen - Frontiers in immunology, 2019 - frontiersin.org
The concept of immunizing against gonorrhea has received renewed interest because of the
recent emergence of strains of Neisseria gonorrhoeae that are resistant to most currently …
recent emergence of strains of Neisseria gonorrhoeae that are resistant to most currently …
CEACAM1 structure and function in immunity and its therapeutic implications
The type I membrane protein receptor carcinoembryonic antigen-related cell adhesion
molecule 1 (CEACAM1) distinctively exhibits significant alternative splicing that allows for …
molecule 1 (CEACAM1) distinctively exhibits significant alternative splicing that allows for …
Experimental vaccine induces Th1-driven immune responses and resistance to Neisseria gonorrhoeae infection in a murine model
Y Liu, LA Hammer, W Liu, MM Hobbs, RA Zielke… - Mucosal …, 2017 - nature.com
Female mice were immunized intravaginally with gonococcal outer membrane vesicles
(OMVs) plus microencapsulated interleukin-12 (IL-12), and challenged using an established …
(OMVs) plus microencapsulated interleukin-12 (IL-12), and challenged using an established …
Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody
S Gulati, FJ Beurskens, BJ de Kreuk, M Roza… - PLoS …, 2019 - journals.plos.org
Multidrug-resistant Neisseria gonorrhoeae is a global health problem. Monoclonal antibody
(mAb) 2C7 recognizes a gonococcal lipooligosaccharide epitope that is expressed by> 95 …
(mAb) 2C7 recognizes a gonococcal lipooligosaccharide epitope that is expressed by> 95 …
Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract: neutrophilic host response, sustained infection, and clinical sequelae
JS Stevens, AK Criss - Current opinion in hematology, 2018 - journals.lww.com
Pathogenesis of Neisseria gonorrhoeae in the female reproduc... : Current Opinion in
Hematology Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract …
Hematology Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract …
The E-cadherin cleavage associated to pathogenic bacteria infections can favor bacterial invasion and transmigration, dysregulation of the immune response and …
Once bound to the epithelium, pathogenic bacteria have to cross epithelial barriers to invade
their human host. In order to achieve this goal, they have to destroy the adherens junctions …
their human host. In order to achieve this goal, they have to destroy the adherens junctions …