Biomaterials delivery strategies to repair spinal cord injury by modulating macrophage phenotypes
Y Xia, R Yang, H Wang, Y Hou, Y Li… - Journal of tissue …, 2022 - journals.sagepub.com
Spinal cord injury (SCI) causes tremendous harm to a patient's physical, mental, and
financial health. Moreover, recovery of SCI is affected by many factors, inflammation is one …
financial health. Moreover, recovery of SCI is affected by many factors, inflammation is one …
[HTML][HTML] Sustained delivery of neurotrophic factors to treat spinal cord injury
A Muheremu, L Shu, J Liang, A Aili… - Translational …, 2021 - degruyter.com
Acute spinal cord injury (SCI) is a devastating condition that results in tremendous physical
and psychological harm and a series of socioeconomic problems. Although neurons in the …
and psychological harm and a series of socioeconomic problems. Although neurons in the …
The effect of a nanofiber-hydrogel composite on neural tissue repair and regeneration in the contused spinal cord
An injury to the spinal cord causes long-lasting loss of nervous tissue because endogenous
nervous tissue repair and regeneration at the site of injury is limited. We engineered an …
nervous tissue repair and regeneration at the site of injury is limited. We engineered an …
Developing a mechanically matched decellularized spinal cord scaffold for the in situ matrix-based neural repair of spinal cord injury
Y Ma, H Shi, Q Wei, Q Deng, J Sun, Z Liu, B Lai, G Li… - Biomaterials, 2021 - Elsevier
Tissue engineering is a promising strategy to repair spinal cord injury (SCI). However, a
bioscaffold with mechanical properties that match those of the pathological spinal cord …
bioscaffold with mechanical properties that match those of the pathological spinal cord …
[HTML][HTML] Double crosslinked biomimetic composite hydrogels containing topographical cues and WAY-316606 induce neural tissue regeneration and functional …
X Zhao, X Lu, K Li, S Song, Z Luo, C Zheng, C Yang… - Bioactive Materials, 2023 - Elsevier
Spinal cord injury (SCI) is an overwhelming and incurable disabling condition, for which
increasing forms of multifunctional biomaterials are being tested, but with limited …
increasing forms of multifunctional biomaterials are being tested, but with limited …
A combination of mesenchymal stem cells and scaffolds promotes motor functional recovery in spinal cord injury: a systematic review and meta-analysis
OBJECTIVE There is controversy about the role of scaffolds as an adjunctive therapy to
mesenchymal stem cell (MSC) transplantation in spinal cord injury (SCI). Thus, the authors …
mesenchymal stem cell (MSC) transplantation in spinal cord injury (SCI). Thus, the authors …
[HTML][HTML] Complete rat spinal cord transection as a faithful model of spinal cord injury for translational cell transplantation
D Lukovic, V Moreno-Manzano, E Lopez-Mocholi… - Scientific reports, 2015 - nature.com
Spinal cord injury (SCI) results in neural loss and consequently motor and sensory
impairment below the injury. There are currently no effective therapies for the treatment of …
impairment below the injury. There are currently no effective therapies for the treatment of …
[HTML][HTML] Biocompatibility of reduced graphene oxide nanoscaffolds following acute spinal cord injury in rats
AH Palejwala, JS Fridley, JA Mata… - Surgical neurology …, 2016 - ncbi.nlm.nih.gov
Background: Graphene has unique electrical, physical, and chemical properties that may
have great potential as a bioscaffold for neuronal regeneration after spinal cord injury …
have great potential as a bioscaffold for neuronal regeneration after spinal cord injury …
The combined strategy of mesenchymal stem cells and tissue-engineered scaffolds for spinal cord injury regeneration
P Bramanti, E Mazzon - … and Therapeutic Medicine, 2017 - spandidos-publications.com
Spinal cord injury (SCI) is a traumatic lesion that can result in the loss of motor or sensory
neurons. Stem cell (SC)‑based therapies have been demonstrated to promote neuronal …
neurons. Stem cell (SC)‑based therapies have been demonstrated to promote neuronal …
Functional recovery in spinal cord injured rats using polypyrrole/iodine implants and treadmill training
Currently, there is no universally accepted treatment for traumatic spinal cord injury (TSCI), a
pathology that can cause paraplegia or quadriplegia. Due to the complexity of TSCI, more …
pathology that can cause paraplegia or quadriplegia. Due to the complexity of TSCI, more …