Background Use of sedatives may increase risk of death in opioid users. The aim of the
study was to assess whether prescription of sedatives may be associated with mortality in …

Background: Although awareness of the misuse of medicines is increasing, data on the
extent of the problem in the European Union (EU) are lacking. Methods: In order to assess …

Internet and digital technologies have been discussed recently by Addiction contributors in
relation to the delivery of efficient computer-delivered brief interventions, online …

Discovered in the late 1950s by Leo Sternbach, the first benzodiazepine (BZD)
chlordiazepoxide was followed by several congeners, which rapidly constituted one of the …

Globally benzodiazepines remain one of the most prescribed medication groups, especially
in the primary care setting. With such high levels of prescribing it is not surprising that …

Aim The aim of this study was to describe the incidence of morbidities and the prevalence of
medical prescriptions in a large Down syndrome population. Method A retrospective cohort …

This chapter reviews the role of benzodiazepines (BZs) in the treatment of anxiety disorders,
specifically panic disorder with or without agoraphobia, generalized anxiety disorder, and …

Background Conventional drug treatments for Generalized Anxiety Disorder (GAD) are often
accompanied by substantial side effects, dependence, and/or withdrawal syndrome. A prior …

Modern neuropsychopharmacology commenced in the 1950s with the serendipitous
discovery of first-generation antipsychotics and antidepressants which were therapeutically …

Background Benzodiazepine abuse and dependence have been recognized and widely
discussed for more than 40 years. With more than 230 million daily doses prescribed in …