There have been significant advancements in the pharmacologic management of
posttraumatic stress disorder (PTSD) in the past two decades. Multisite randomized clinical …

O presente estudo buscou compreender aspectos assistenciais presentes na base da
utilização indiscriminada de benzodiazepínicos. Com base numa parceria entre uma …

Chronic insomnia occurs in~ 10% of the general population and has numerous negative
health effects. The recommended first line treatment of cognitive behavior therapy for …

Benzodiazepines and Z-drugs are commonly prescribed for insomnia and anxiety
syndromes and there is increasing concern regarding their misuse. Using an internet-based …

Objective: The authors investigated the frequency and determinants of long-term use and
risk of dose escalation of benzodiazepines and benzodiazepine-related drugs …

Background Pharmacoepidemiological studies have long raised concerns on widespread
use of benzodiazepines and benzodiazepine-related drugs (BZDs), in particular long-term …

Objective We performed a systematic review and meta-analysis of double-blind,
randomized, placebo-controlled trials evaluating suvorexant for primary insomnia. Methods …

Context: The relationship between benzodiazepine consumption and subsequent increases
in aggressive behaviour in humans is not well understood. Objectives: The current study …

Background: Over 92 million prescriptions for benzodiazepines are dispensed in the United
States annually, yet little is known about the experiences of those taking and discontinuing …

Background Acute benzodiazepine withdrawal has been described, but literature regarding
the benzodiazepine-induced neurological injury that may result in enduring symptoms and …