This review highlights the nature, characteristics, properties, pharmacological differences
between different types of benzodiazepines, the mechanism of action in the central nervous …

Neurological drugs are often associated with serious side effects, yet drug screens typically
focus only on efficacy. We demonstrate a novel paradigm utilizing high-throughput in vivo …

Low doses of the antidepressant mirtazapine or the neuroleptic quetiapine are often
prescribed off-label for insomnia. However, studies on the effects on sleep and hangover …

The large class of CNS-depressant medications—the benzodiazepines—have been
extensively used for over 50 years, anxiety disorders being one of the main indications. A …

Background Over the past decade, patients admitted to addiction treatment programs have
reported increasing rates of concurrent opioid and benzodiazepine (BZD) use. This drug …

Up to 70% of persons living with HIV (PLWH) experience sleep disturbances. Insomnia and
obstructive sleep apnea syndrome (OSAS) are common disorders seen in the primary care …

Abstract Background Benzodiazepines (BZDs) are widely prescribed during psychiatric
treatment. Unfortunately, their misuse has led to recent surges in overdose emergency visits …

Objective: This study aimed to determine the prevalence of benzodiazepine (BZD) use in
Brazil and to investigate the direct and indirect effects of alcohol consumption, sedentary …

Background: Benzodiazepine treatment recommendations for older adults differ markedly
between guidelines, especially their advice on the acceptability of long-term use. Aims …

Chemical coping is a working definition that describes patients' intake of opioids on a scale
that spans the range between normal nonaddictive opioid use for pain all the way to opioid …