Objective Patients with chronic insomnia are prone to long-term use of hypnotics. Reported
risk factors include aging, female sex, and comorbid psychiatric disorders. However, most …

Background Understanding how patients are treated in the real-world is vital to identifying
potential gaps in care. We describe the current pharmacologic treatment patterns for the …

ETHNOPHARMACOLOGICAL RELEVANCE: Wuling Capsule is a single herbal formula
from mycelia of precious Xylaria nigripes (Kl.) Sacc and its pharmacological function have a …

Aims Benzodiazepines (BZD s) are effective in the short term against anxiety and insomnia.
However, some BZD users develop BZD dependence after a relatively short period of time …

Acute benzodiazepine intoxication produces severe impairment of neurocognitive skills
related to driving. It is less clear whether such impairments also occur in patients who use …

BACKGROUND: Although the Veterans Affairs and Department of Defense (VA/DoD) clinical
guidelines for management of posttraumatic stress disorder (PTSD) recommend against …

Background: Drunk or drug-impaired drivers represent a major public health and societal
problem worldwide. Because over 95% of drivers killed on the roads in Sweden are …

Background Central nervous system depressant medications (CNSDs) such as opioid
analgesics and sedative-hypnotics are commonly prescribed to older patients for the …

Objective: To identify risk factors for becoming an excessive user over time. Setting:
Prescription database study over five years. Subjects and method: Norwegians between 30 …

Background The current standard of care for insomnia includes gamma-aminobutyric acid
receptor A (GABA A) activators, which promote sleep as well as general central nervous …