Design of Experiments (DoE) is a statistical tool used to plan and optimize experiments and
is seen as a quality technology to achieve products excellence. Among the experimental …

The present study aimed to analyze how the printing process affects the final state of a
printed pharmaceutical product and to establish prediction models for post-printing …

Clobetasol propionate (CLO) is a potent glucocorticoid used to treat inflammation-based
skin, scalp, and hair disorders. In such conditions, hair follicles (HF) are not only the target …

Solid inclusion complexes with cyclodextrins (CD) may be used to overcome volatility and
solubility problems of essential oils of pharmacological interest. However, they lack the …

Alopecia is a condition associated with different etiologies, ranging from hormonal changes
to chemotherapy, that affects over 80 million people in the USA. Nevertheless, there are …

The present work is focused on the development of novel surface-functionalized poly (lactic-
co-glycolic acid) nanoparticles loaded with thymol (TH-NPs) for topical administration …

The flavonoid naringenin (NAR) exhibits an outstanding anti-inflammatory potential;
however, stability problems and reduced solubility hinder its commercial insertion. This work …

The complexation of cyclodextrin ranks among the best methods of overcoming the
unfavorable pharmacokinetic properties of naringenin (NAR). This work proposes obtaining …

This study aimed to investigate whether hot-melt extrusion (HME) processing can modify the
interactions between drugs, cyclodextrins and polymers, and in turn alter the microstructure …

This study sought to develop polymer-lipid hybrid solid dispersions containing the poorly
soluble drug lopinavir (LPV) by hot-melt extrusion (HME). Hence, the lipid and polymeric …