Second‐generation antipsychotics and extrapyramidal adverse effects

N Divac, M Prostran, I Jakovcevski… - BioMed research …, 2014 - Wiley Online Library
Antipsychotic‐induced extrapyramidal adverse effects are well recognized in the context of
first‐generation antipsychotic drugs. However, the introduction of second‐generation …

Molecular targets of atypical antipsychotics: From mechanism of action to clinical differences

S Aringhieri, M Carli, S Kolachalam, V Verdesca… - Pharmacology & …, 2018 - Elsevier
The introduction of atypical antipsychotics (AAPs) since the discovery of its prototypical drug
clozapine has been a revolutionary pharmacological step for treating psychotic patients as …

[图书][B] The American Psychiatric Association practice guideline for the treatment of patients with schizophrenia

American Psychiatric Association - 2020 - books.google.com
The American Psychiatric Association Practice Guideline for the Treatment of Patients With
Schizophrenia seeks to reduce these substantial psychosocial and public health …

KINECT 3: a phase 3 randomized, double-blind, placebo-controlled trial of valbenazine for tardive dyskinesia

RA Hauser, SA Factor, SR Marder… - American Journal of …, 2017 - Am Psychiatric Assoc
Objective: Tardive dyskinesia is a persistent movement disorder induced by dopamine
receptor blockers, including antipsychotics. Valbenazine (NBI-98854) is a novel, highly …

Tardive dyskinesia risk with first‐and second‐generation antipsychotics in comparative randomized controlled trials: a meta‐analysis

M Carbon, JM Kane, S Leucht, CU Correll - World Psychiatry, 2018 - Wiley Online Library
Tardive dyskinesia (TD) risk with D2/serotonin receptor antagonists or D2 receptor partial
agonists (second‐generation antipsychotics, SGAs) is considered significantly lower than …

Deutetrabenazine for treatment of involuntary movements in patients with tardive dyskinesia (AIM-TD): a double-blind, randomised, placebo-controlled, phase 3 trial

KE Anderson, D Stamler, MD Davis, SA Factor… - The Lancet …, 2017 - thelancet.com
Background Tardive dyskinesia results from exposure to dopamine receptor antagonists,
such as typical and atypical antipsychotics. If clinically appropriate, clinicians often manage …

Randomized controlled trial of deutetrabenazine for tardive dyskinesia: the ARM-TD study

HH Fernandez, SA Factor, RA Hauser… - Neurology, 2017 - AAN Enterprises
Objective: To determine the efficacy and safety of deutetrabenazine as a treatment for
tardive dyskinesia (TD). Methods: One hundred seventeen patients with moderate to severe …

“First do no harm.” A systematic review of the prevalence and management of antipsychotic adverse effects

SL Young, M Taylor, SM Lawrie - Journal of …, 2015 - journals.sagepub.com
Aims: We aim to identify the prevalence and management strategies of nine clinically
important categories of antipsychotic adverse effects, namely: extrapyramidal symptoms; …

Antipsychotic-related movement disorders: drug-induced parkinsonism vs. tardive dyskinesia—key differences in pathophysiology and clinical management

KM Ward, L Citrome - Neurology and therapy, 2018 - Springer
Introduction Drug-induced parkinsonism (DIP) and tardive dyskinesia (TD) are stigmatizing
movement disorders associated with exposure to dopamine receptor blocking agents such …

[图书][B] The bitterest pills: The troubling story of antipsychotic drugs

J Moncrieff - 2013 - books.google.com
Page 1 Joanna Moncrieff Author of The Myth of º the Chemical Cure THE CBITTEREST The
Troubling Story of Antipsychotic Drugs * Page 2 The Bitterest Pills Page 3 Also by Joanna …