The association and significance of p53 in gynecologic cancers: the potential of targeted therapy

M Nakamura, T Obata, T Daikoku… - International Journal of …, 2019 - mdpi.com
Dysfunction of p53 is observed in the many malignant tumors. In cervical cancer, p53 is
inactivated by degradation through the complex with human papilloma virus (HPV) …

Molecular mechanisms of oestrogen and SERMs in endometrial carcinogenesis

Y Shang - Nature Reviews Cancer, 2006 - nature.com
Endometrial cancer is the most common gynaecological cancer, and is associated with
endometrial hyperplasia, unopposed oestrogen exposure and adjuvant therapy for breast …

Clinicopathologic and molecular characteristics of mesonephric adenocarcinoma arising from the uterine body

K Na, HS Kim - The American journal of surgical pathology, 2019 - journals.lww.com
Mesonephric adenocarcinoma (MNAC) is a rare tumor of the female genital tract mainly
occurring in the uterine cervix. To date, only a few cases of MNAC arising from of the uterine …

Endometrial carcinoma: pathology and genetics

J Prat, A Gallardo, M Cuatrecasas, L Catasús - Pathology, 2007 - Taylor & Francis
In the Western world, endometrial carcinoma is the most common malignant tumour of the
female genital tract and the fourth most common cancer in women after carcinomas of …

Endometrioid carcinoma of the uterine corpus: a review of its pathology with emphasis on recent advances and problematic aspects

PB Clement, RH Young - Advances in anatomic pathology, 2002 - journals.lww.com
This review considers the pathologic features of endometrioid carcinoma of the uterine
corpus, which accounts for approximately 80% of endometrial adenocarcinomas, with an …

[图书][B] Diagnosis of endometrial biopsies and curettings: a practical approach

M Mazur, RJ Kurman - 2005 - books.google.com
DIAGNOSIS OF ENDOMETRIAL BIOPSIES, Second Edition, revised and now with color
illustrations, continues the tradition as being the most concise and complete diagnostic …

Should grade 3 endometrioid endometrial carcinoma be considered a type 2 cancer—a clinical and pathological evaluation

MA Voss, R Ganesan, L Ludeman, K McCarthy… - Gynecologic …, 2012 - Elsevier
OBJECTIVE: Endometrial cancer is classified into: Type I estrogen-dependent endometrioid
adenocarcinoma, with good prognosis and type 2 non-estrogen-dependent cancer with …

Endometrial cancer

AJ Ryan, B Susil, TW Jobling, MK Oehler - Cell and tissue research, 2005 - Springer
Endometrial cancer is the most common gynaecological malignancy in the developed world.
The majority of cases can be divided into two broad categories based on clinico …

Apoptosis and apoptosis‐related factors Bcl‐2, Bax, tumor necrosis factor‐α, and NF‐κB in human endometrial hyperplasia and carcinoma

TE Vaskivuo, F Stenbäck, JS Tapanainen - Cancer, 2002 - Wiley Online Library
BACKGROUND Apoptosis controls cell homeostasis in the endometrium during normal
menstrual cycles, and morphologic studies have suggested its association with the …

Frequent expression of napsin A in clear cell carcinoma of the endometrium: potential diagnostic utility

O Fadare, MM Desouki, K Gwin… - The American journal …, 2014 - journals.lww.com
The histotyping of high-grade endometrial carcinomas with clear cells may be subject to
significant interobserver variability, which suggests that a biomarker that can distinguish …