Although the introduction of universal pertussis immunisation in infants has greatly reduced
the number of reported cases in infants and young children, disease incidence has been …

Pertussis is resurgent in some countries, particularly those in which children receive
acellular pertussis (aP) vaccines in early infancy and boosters later in life. Immunologic …

This report compiles and summarizes all recommendations from CDC's Advisory Committee
on Immunization Practices (ACIP) regarding prevention and control of tetanus, diphtheria …

Background Two Tdap vaccines are licensed for use in the United States. Boostrix
(GlaxoSmithKline) is approved for a single dose in persons aged≥ 10 years; Adacel (Sanofi …

Pertussis is one of the most prevalent vaccine-preventable diseases worldwide. The true
infection rate is significantly higher than the reported incidence rate. An increased …

The UK is currently in the midst of a large outbreak of pertussis, with the highest morbidity
and mortality occurring in young unimmunised infants. This review considers the potential …

Adult booster immunization, either universal or targeted (mothers during pregnancy or
'cocoon'), would probably be effective but is challenging to implement. If shown to be safe …

Combination vaccines containing a monocomponent acellular pertussis (aP) vaccine,
manufactured at Statens Serum Institut (SSI), Denmark, have successfully controlled …

The measurement of IgG anti-pertussis toxin (IgG anti-PT) antibodies by ELISA is a
frequently used method for studying the antibody responses after pertussis vaccination and …

Pertussis is a highly contagious infectious disease caused by Bordetella pertussis that can
be extremely serious, particularly in young infants. For many years the efforts of health …