Ageing organisms accumulate senescent cells that are thought to contribute to body
dysfunction. Telomere shortening and damage are recognized causes of cellular …

Osteoporosis is characterized by the alteration of bone homeostasis due to an imbalance
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …

Osteoporosis is caused by the disruption in homeostasis between bone formation and bone
resorption. Conventional management of osteoporosis involves systematic drug …

Ageing is the biggest risk factor for impaired cardiovascular health, with cardiovascular
disease being the cause of death in 40% of individuals over 65 years old. Ageing is …

Age-related chronic diseases are an enormous burden to modern societies worldwide.
Among these, osteoporosis, a condition that predisposes individuals to an increased risk of …

Osteoporosis does not only affect postmenopausal women, but also ageing men. The
burden of disease is projected to increase with higher life expectancy both in females and …

Senile osteoporosis is one of the major health problems in an aging society. Decreased
bone formation due to osteoblast dysfunction may be one of the causes of aging-related …

The pace of bone formation slows down with aging, which leads to the development of
osteoporosis. In addition to senescent bone marrow mesenchymal stem cells (S-BMSCs) …

Much of paleodemography, an interdisciplinary field with strong ties to archaeology, among
other disciplines, is oriented toward clarifying the life experiences of past people and why …

Mesenchymal stromal cells (MSC) have been proposed as an emerging cell-based
therapeutic option for regenerative medicine applications as these cells can promote tissue …