[HTML][HTML] Eriocitrin: A review of pharmacological effects

L Yao, W Liu, M Bashir, MF Nisar, CC Wan - Biomedicine & …, 2022 - Elsevier
The present study aimed to recognize the recent literature to highlight the pharmacological
impacts and highlight the therapeutic potential of the active molecule eriocitrin. Citrus limon …

Small molecules as a source for acute kidney injury therapy

YL Feng, Y Yang, H Chen - Pharmacology & Therapeutics, 2022 - Elsevier
Acute kidney injury (AKI) is a sudden loss of kidney function that causes a rise in serum
creatinine and a decrease in urine output, which leads to high morbidity and mortality …

Eriocitrin attenuates sepsis-induced acute lung injury in mice by regulating MKP1/MAPK pathway mediated-glycolysis

D Li, L Yang, W Wang, C Song, R Xiong, S Pan… - International …, 2023 - Elsevier
Metabolic reprogramming has been shown to aggravate sepsis-induced acute lung injury. In
particular, enhanced glycolysis is closely associated with inflammation and oxidative stress …

Unravelling the Untapped Pharmacological Potential of Plant Molecules as Inhibitors of BACE1: In Silico Explorations for Alzheimer's Disease

K Kalaimathi, S Prabhu, M Ayyanar… - Applied Biochemistry …, 2023 - Springer
Alzheimer's disease (AD) is an extremely complex, heterogeneous, and multifactorial
neurodegenerative disease clinically characterized by progressive memory loss and …

CircTLK1 alleviates oxygen-glucose deprivation/reperfusion induced apoptosis in HK-2 cells through miR-136-5p/Bcl2 signal axis

L Kuang, A Lu, S Yao - Renal Failure, 2023 - Taylor & Francis
The biological functions of circTLK1 in acute kidney injury (AKI), which mainly results from
renal ischemia-reperfusion (IR), remain largely unknown. HK-2 cell treatment with oxygen …

UPLC-QTOF-MS with a chemical profiling approach for holistic quality evaluation between a material reference of Wen Dan decoction and its commercial preparations

S Yang, G Chen, M Yuan, Y Zou, H Zhang, H Xu - Chinese Medicine, 2023 - Springer
Abstract Background Wen Dan decoction (WDD) has been a famous classic formula for
resolving phlegm since ancient times in China. Currently, there are many types of WDD …

In Vitro Antiglycation and Methylglyoxal Trapping Effect of Peppermint Leaf (Mentha × piperita L.) and Its Polyphenols

I Fecka, K Bednarska, A Kowalczyk - Molecules, 2023 - mdpi.com
The most significant reactive α-dicarbonyl RCS involved in the pathomechanism of glycation
and related diseases is methylglyoxal (MGO). Hyperglycemia promotes the generation of …

Dual-specificity phosphatases and kidney diseases

H Li, J Xiong, Y Du, Y Huang, J Zhao - Kidney Diseases, 2022 - karger.com
Abstract Background: Dual-specificity phosphatases (DUSPs) belong to the family of protein
tyrosine phosphatases, which can dephosphorylate both serine/threonine and tyrosine …

[HTML][HTML] TRPC6 ameliorates renal ischemic reperfusion injury by inducing Zn2+ influx and activating autophagy to resist necrosis

Y Pu, H Zhao, B Shen, Q Zhou, P Xie… - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Background Renal ischemic reperfusion injury (RIRI) is the most hackneyed cause of acute
renal injury with high incidence. As a slit diaphragm (SD), TRPC6 (transient receptor …

[HTML][HTML] Industrial-produced lemon nanovesicles ameliorate experimental colitis-associated damages in rats via the activation of anti-inflammatory and antioxidant …

V Tinnirello, MG Zizzo, A Conigliaro, M Tabone… - Biomedicine & …, 2024 - Elsevier
Plant-derived nanovesicles (PDNVs) have recently emerged as natural delivery systems of
biofunctional compounds toward mammalian cells. Considering their already described …