Hyperglycemia and oxidative stress: An integral, updated and critical overview of their metabolic interconnections

P González, P Lozano, G Ros, F Solano - International Journal of …, 2023 - mdpi.com
This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …

Antioxidant defence systems and oxidative stress in poultry biology: An update

PF Surai, II Kochish, VI Fisinin, MT Kidd - Antioxidants, 2019 - mdpi.com
Poultry in commercial settings are exposed to a range of stressors. A growing body of
information clearly indicates that excess ROS/RNS production and oxidative stress are …

The role of sirtuins in antioxidant and redox signaling

CK Singh, G Chhabra, MA Ndiaye… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Antioxidant and redox signaling (ARS) events are regulated by critical
molecules that modulate antioxidants, reactive oxygen species (ROS) or reactive nitrogen …

[HTML][HTML] The world of protein acetylation

A Drazic, LM Myklebust, R Ree, T Arnesen - Biochimica et Biophysica Acta …, 2016 - Elsevier
Acetylation is one of the major post-translational protein modifications in the cell, with
manifold effects on the protein level as well as on the metabolome level. The acetyl group …

Ageing and osteoarthritis

PK Sacitharan - Biochemistry and cell biology of ageing: part II clinical …, 2019 - Springer
The increase in global lifespan has in turn increased the prevalence of osteoarthritis which
is now the most common type of arthritis. Cartilage tissue located on articular joints erodes …

Senescence in osteoarthritis: from mechanism to potential treatment

Y Liu, Z Zhang, T Li, H Xu, H Zhang - Arthritis Research & Therapy, 2022 - Springer
Osteoarthritis (OA) is an age-related cartilage degenerative disease, and chondrocyte
senescence has been extensively studied in recent years. Increased numbers of senescent …

The role of reactive oxygen species in arsenic toxicity

Y Hu, J Li, B Lou, R Wu, G Wang, C Lu, H Wang, J Pi… - Biomolecules, 2020 - mdpi.com
Arsenic poisoning is a global health problem. Chronic exposure to arsenic has been
associated with the development of a wide range of diseases and health problems in …

Impact of oxidative stress on age-associated decline in oocyte developmental competence

H Sasaki, T Hamatani, S Kamijo, M Iwai… - Frontiers in …, 2019 - frontiersin.org
Reproductive capacity in women starts to decline beyond their mid-30s and pregnancies in
older women result in higher rates of miscarriage with aneuploidy. Age-related decline in …

Sirtuins, a promising target in slowing down the ageing process

W Grabowska, E Sikora, A Bielak-Zmijewska - Biogerontology, 2017 - Springer
Ageing is a plastic process and can be successfully modulated by some biomedical
approaches or pharmaceutics. In this manner it is possible to delay or even prevent some …

[HTML][HTML] The hallmarks of aging

C López-Otín, MA Blasco, L Partridge, M Serrano… - Cell, 2013 - cell.com
Aging is characterized by a progressive loss of physiological integrity, leading to impaired
function and increased vulnerability to death. This deterioration is the primary risk factor for …