Alzheimer disease (AD) is the most common contributor to dementia in the world, but
strategies that slow or prevent its clinical progression have largely remained elusive, until …

Alzheimer's disease (AD) is the most common cause of dementia worldwide, and its
prevalence is rapidly increasing due to extended lifespans. Among the increasing number of …

Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder with
multifaceted neuropathological features, including β-amyloid plaques, neurofibrillary …

Mild Alzheimer's disease is the leading cause of dementia, accounting for 50–70% of cases.
Alzheimer's disease is an irreversible neurodegenerative disease, which affects daily life …

Sleep is a complex physiological process and is a critical determinant of physical and
mental health. In the past decades, significant progress has been made in understanding …

Importance Disrupted sleep is common in aging and is associated with cognition. Age-
related changes to sleep are associated with multiple causes, including early Alzheimer …

Sleep plays an important role in maintaining neuronal circuitry, signalling and helps
maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian …

In the past decade, evidence for a fluid clearance pathway in the central nervous system
known as the glymphatic system has grown. According to the glymphatic system concept …

Sleep is entwined across many physiologic processes in the brain and periphery, thereby
exerting tremendous influence on our well-being. Yet sleep exists in a social-environmental …

Causal machine learning (CML) has experienced increasing popularity in healthcare.
Beyond the inherent capabilities of adding domain knowledge into learning systems, CML …