Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions
C Qin, S Yang, YH Chu, H Zhang, XW Pang… - Signal transduction and …, 2022 - nature.com
Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …
severe neural injuries, and is one of the leading causes of death and disability worldwide …
A dynamic DNA tetrahedron framework for active targeting
An active targeting strategy-enabled DNA tetrahedron delivery vehicle could facilitate stable
drug encapsulation and stimuli-responsive on-demand release, building a universal …
drug encapsulation and stimuli-responsive on-demand release, building a universal …
Modulation of the crosstalk between Schwann cells and macrophages for nerve regeneration: a therapeutic strategy based on a multifunctional tetrahedral framework …
J Li, Y Yao, Y Wang, J Xu, D Zhao, M Liu… - Advanced …, 2022 - Wiley Online Library
Peripheral nerve injury (PNI) is currently recognized as one of the most significant public
health issues and affects the general well‐being of millions of individuals worldwide …
health issues and affects the general well‐being of millions of individuals worldwide …
Typhaneoside-tetrahedral framework nucleic acids system: mitochondrial recovery and antioxidation for acute kidney injury treatment
R Yan, W Cui, W Ma, J Li, Z Liu, Y Lin - ACS nano, 2023 - ACS Publications
Acute kidney injury (AKI) is not only a worldwide problem with a cruel hospital mortality rate
but also an independent risk factor for chronic kidney disease and a promoting factor for its …
but also an independent risk factor for chronic kidney disease and a promoting factor for its …
Prospects and challenges of dynamic DNA nanostructures in biomedical applications
T Tian, Y Li, Y Lin - Bone Research, 2022 - nature.com
The physicochemical nature of DNA allows the assembly of highly predictable structures via
several fabrication strategies, which have been applied to make breakthroughs in various …
several fabrication strategies, which have been applied to make breakthroughs in various …
Myelosuppression alleviation and hematopoietic regeneration by tetrahedral‐framework nucleic‐acid nanostructures functionalized with osteogenic growth peptide
T Zhang, M Zhou, D Xiao, Z Liu, Y Jiang… - Advanced …, 2022 - Wiley Online Library
As major complications of chemoradiotherapy, myelosuppression and hematopoietic‐
system damage severely affect immunologic function and can delay or even terminate …
system damage severely affect immunologic function and can delay or even terminate …
Antiepilepticus effects of tetrahedral framework nucleic acid via inhibition of gliosis-induced downregulation of glutamine synthetase and increased AMPAR …
J Zhu, Y Yang, W Ma, Y Wang, L Chen, H Xiong… - Nano Letters, 2022 - ACS Publications
More than 15 million out of 70 million patients worldwide do not respond to available
antiepilepticus drugs (AEDs). With the emergence of nanomedicine, nanomaterials are …
antiepilepticus drugs (AEDs). With the emergence of nanomedicine, nanomaterials are …
Suppression of lipopolysaccharide‐induced sepsis by tetrahedral framework nucleic acid loaded with quercetin
Z Liu, X Chen, W Ma, Y Gao, Y Yao, J Li… - Advanced Functional …, 2022 - Wiley Online Library
Sepsis has affected millions of people worldwide with high mortality rate and lack of effective
strategies. Previous studies have reported that quercetin (Que) can attenuate …
strategies. Previous studies have reported that quercetin (Que) can attenuate …
Stroke: Molecular mechanisms and therapies: Update on recent developments
F Shehjar, B Maktabi, ZA Rahman, GA Bahader… - Neurochemistry …, 2023 - Elsevier
Stroke, a neurological disease, is one of the leading causes of death worldwide, resulting in
long-term disability in most survivors. Annual stroke costs in the United States alone were …
long-term disability in most survivors. Annual stroke costs in the United States alone were …
[HTML][HTML] Autologous exosome facilitates load and target delivery of bioactive peptides to repair spinal cord injury
N Ran, W Li, R Zhang, C Lin, J Zhang, Z Wei, Z Li… - Bioactive Materials, 2023 - Elsevier
Spinal cord injury (SCI) causes motor, sensory and automatic impairment due to rarely axon
regeneration. Developing effective treatment for SCI in the clinic is extremely challenging …
regeneration. Developing effective treatment for SCI in the clinic is extremely challenging …