Neurotrophic factors comprise essential secreted proteins that have several functions in
neural and non-neural tissues, mediating the development, survival and maintenance of …

Epidemiological studies indicate that physical activity and exercise may reduce the risk of
developing Parkinson's disease (PD), and clinical observations suggest that physical …

Although the basal ganglia play an important role in self‐generated movement, their
involvement in externally paced voluntary movement is less clear. We recorded local field …

Previous studies have used recombinant adeno-associated viral (rAAV) vectors to deliver
glial cell line-derived neurotrophic factor (GDNF) in the substantia nigra to protect the nigral …

The distribution of nerve growth factor (NGF), ciliary neurotrophic factor (CNTF), glial cell line-
derived neurotrophic factor (GDNF), brain derived neurotrophic factor (BDNF), neurotrophin …

Intrastriatal 6-hydroxydopamine injections in rats induce partial lesions of the nigrostriatal
dopamine (DA) system which are accompanied by a delayed and protracted degeneration …

Both glial cell line‐derived neurotrophic factor (GDNF) and its recently discovered congener,
neurturin (NTN), have been shown to excert neuroprotective effects on lesioned nigral …

The therapeutic potential of glial cell line-derived neurotrophic factor (GDNF) for Parkinson's
disease is likely to depend on sustained delivery of the appropriate amount to the target …

Here we studied whether glial cell line‐derived neurotrophic factor (GDNF), given as a
single bolus injection before an intrastriatal 6‐hydroxydopamine (6‐OHDA) lesion, can …

The present study examined a role for GDNF in adaptations to drugs of abuse. Infusion of
GDNF into the ventral tegmental area (VTA), a dopaminergic brain region important for …