Chronic kidney disease (CKD) is an important health concern that is expected to be the fifth
most widespread cause of death worldwide by 2040. The presence of chronic inflammation …

Renal fibrosis is a common result for various chronic kidney diseases developing to the end
stage. It is a pathological process characterized by the destruction of normal kidney structure …

Objective To study the effect of ShenKang Injection (SKI) on the kidneys of DKD rats and its
effect on oxidative stress mediated by the Keap1/Nrf2/Ho-1 signaling pathway through …

CKD is a global health concern with significant implications for patients' well-being,
morbidity, and mortality. The underlying mechanism of CKD development often involves …

Objective To explore the potential mechanism of Shenkang injection (SKI) in the treatment of
chronic renal failure based on network pharmacology and molecular docking technology …

This research was aimed to investigate the effect of circPTPN4 overexpression in
carboxylated single-walled carbon nanotubes (SWCNT-COOH) on renal fibrosis (RF) in …

The activation of hepatic stellate cells (HSCs) has proved to be pivotal in hepatic fibrosis.
Therefore, the suppression of HSC activation is an effective anti-fibrotic strategy. Although …

Objective To systematically evaluate the clinical efficacy and safety of Shenkang injection
(SKI) combined with alprostadil in the treatment of chronic renal failure (CRF). Method …

Background Being amongst the leading factors of death and distress, chronic kidney
disease (CKD) has affected around 850 million people globally. The Wnt/β‐catenin axis is …

Chronic kidney disease (CKD) is almost always associated with comorbidities such as
diabetes, hyperuricemia/gout, urolithiasis, often with urinary tract infection, hypertension …