Update from the 5th edition of the World Health Organization classification of head and neck tumors: oropharynx and nasopharynx

C Badoual - Head and neck pathology, 2022 - Springer
The new WHO classification of head and neck tumors provides a comprehensive overview
of lesions by summarizing their clinical, epidemiological, histological, immunohistochemical …

Navigating therapeutic strategies: HPV classification in head and neck cancer

H Tabatabaeian, Y Bai, R Huang, A Chaurasia… - British Journal of …, 2024 - nature.com
Abstract The World Health Organisation recognised human papillomavirus (HPV) as the
cause of multiple cancers, including head and neck cancers. HPV is a double-stranded DNA …

Association of TP53 and CDKN2A Mutation Profile with Tumor Mutation Burden in Head and Neck Cancer

AY Deneka, Y Baca, IG Serebriiskii, E Nicolas… - Clinical Cancer …, 2022 - AACR
Purpose: Head and neck squamous cell carcinoma (HNSCC) is a frequently devastating
cancer that affects more than a half million people annually worldwide. Although some …

Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracellular metabolic reprogramming and activation of oncogenic …

YT Hsieh, HF Tu, MH Yang, YF Chen, XY Lan… - Cell death & …, 2021 - nature.com
Mitochondrial transcriptional factor A (TFAM) acts as a key regulatory to control
mitochondrial DNA (mtDNA); the impact of TFAM and mtDNA in modulating carcinogenesis …

[HTML][HTML] The genomic and evolutionary landscapes of anaplastic thyroid carcinoma

PYF Zeng, SD Prokopec, SY Lai, N Pinto… - Cell reports, 2024 - cell.com
Anaplastic thyroid carcinoma is arguably the most lethal human malignancy. It often co-
occurs with differentiated thyroid cancers, yet the molecular origins of its aggressivity are …

[HTML][HTML] β-catenin/CBP activation of mTORC1 signaling promotes partial epithelial-mesenchymal states in head and neck cancer

ER Reed, SA Jankowski, AJ Spinella, V Noonan… - Translational …, 2023 - Elsevier
Head and neck cancers, which include oral squamous cell carcinoma (OSCC) as a major
subsite, exhibit cellular plasticity that includes features of an epithelial-mesenchymal …

Epidemiology and incidence of oral squamous cell carcinoma in the Iraqi population over 5 years (2014–2018)

ML Alshami, MA Al‐Maliky, AA Alsagban… - Health Science …, 2023 - Wiley Online Library
Background Oral squamous cell carcinoma is one of the most common and life‐threatening
neoplasms worldwide, and is responsible for approximately 90% of all oral malignancies …

Type I conventional dendritic cells and CD8+ T cells predict favorable clinical outcome of head and neck squamous cell carcinoma patients

J Kirchner, I Plesca, R Rothe, A Resag, S Löck… - Frontiers in …, 2024 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is one of the most common tumor
entities worldwide, with human papillomavirus (HPV) infection contributing to cancer …

Investigation of an FGFR-signaling-related prognostic model and immune landscape in head and neck squamous cell carcinoma

Q Chen, L Chu, X Li, H Li, Y Zhang, Q Cao… - Frontiers in Cell and …, 2022 - frontiersin.org
Background: There is accumulating evidence on the clinical importance of the fibroblast
growth factor receptor (FGFR) signal, hypoxia, and glycolysis in the immune …

Laryngeal Anatomy, Molecular Biology, Cause, and Risk Factors for Laryngeal Cancer.

AB Law, NC Schmitt - Otolaryngologic Clinics of North America, 2023 - europepmc.org
Laryngeal cancer is declining in incidence in many parts of the world, as smoking becomes
a less common habit. However, challenging cases of laryngeal cancer still exist and require …