Spray-drying is an inherently continuous and well-established industrial drying process. It
can accelerate manufacturing of biopharmaceuticals and vaccine products, resulting in both …

Oral inhalation results in pulmonary drug targeting and thereby reduces systemic side
effects, making it the preferred means of drug delivery for the treatment of respiratory …

Biorelevant fluids are required to enable meaningful in vitro experimental determinations of
the biopharmaceutical properties of inhaled medicines, eg drug solubility, particle …

Patient compliance will soon become one of the most critical challenges in modern
healthcare. Due in part to our aging population, the rise in the number of chronic conditions …

The number of biologics in the therapeutic development pipeline is increasing including
those delivered though inhalation (Morales, 2017; Fathe, 2016). Biologics comprise a broad …

Dry powder inhalers (DPIs) are regularly used to treat respiratory diseases. Adding extrinsic
fine excipient particles to the blend of active pharmaceutical ingredient (API) and carrier is …

Introduction Leprosy is a neglected, infectious, granulomatous and chronic disease caused
by the pathological agent Mycobacterium leprae. The course of the disease is more …

The pulmonary fate of inhaled poorly water-soluble drugs is not entirely clear. In this study,
the main objective was to investigate the in vivo inhalation biopharmaceutics in the aspects …

The book Pulmonary Drug Delivery Systems: Material and Technological Advances
provides a succinct coverage of the promising technologies and novel materials, which have …

There are few studies in humans dealing with the relationship between physico-chemical
properties of drugs and their systemic bioavailability after administration via oral inhalation …