Did ancestral humans dream for their lives?

A Revonsuo - Behavioral and Brain Sciences, 2000 - cambridge.org
The most challenging objections to the Threat Simulation Theory (TST) of the function of
dreaming include such issues as whether the competing Random Activation Theory can …

[PDF][PDF] Single unit activity of mouse pedunculopontine tegmental nucleus neurons involved in paradoxical (rapid eye movement) sleep generation

K Sakai - Transl Brain Rhythmicity, 2018 - siriusstore.com
The pedunculopontine tegmental nucleus (PPT) contains distinct populations of cholinergic,
glutamatergic, and GABAergic neurons and plays an important role in the control of cortical …

Heterogeneous distribution of the serotonin 5‐HT1A receptor mRNA in chemically identified neurons of the mouse rostral brainstem: Implications for the role of …

P Bonnavion, JF Bernard, M Hamon… - Journal of …, 2010 - Wiley Online Library
Abstract The 5‐HT1A receptor (5‐HT1AR) plays a key role in the inhibitory influence of
serotonin (5‐HT) on rapid eye movement (REM) sleep in rodents. However, the neuronal …

Enhancement of rapid eye movement sleep in the rat by actions at A1 and A2a adenosine receptor subtypes with a differential sensitivity to atropine

GA Marks, JP Shaffery, SG Speciale, CG Birabil - Neuroscience, 2003 - Elsevier
The adenosine agonist cyclohexaladenosine injected into the medial pontine reticular
formation of the rat induces a long-lasting increase in rapid eye movement sleep. To …

Microinjection of neostigmine into the pontine reticular formation of C57BL/6J mouse enhances rapid eye movement sleep and depresses breathing

R Lydic, CL Douglas, HA Baghdoyan - Sleep, 2002 - academic.oup.com
Abstract Study Objectives: The cholinergic model of rapid eye movement (REM) sleep has
contributed significantly to understanding sleep neurobiology and sleep-dependent …

Carbachol and nicotine in prefrontal cortex have differential effects on sleep-wake states

A Parkar, DC Fedrigon, F Alam, G Vanini… - Frontiers in …, 2020 - frontiersin.org
The role of the brainstem cholinergic system in the regulation of sleep-wake states has been
studied extensively but relatively little is known about the role of cholinergic mechanisms in …

Neurochemical modulators of sleep and anesthetic states

CJ Van Dort, HA Baghdoyan… - International …, 2008 - journals.lww.com
The regulation of consciousness is a fundamental question that has a long and storied
association with philosophy. Today, consciousness studies command a central position in …

Hypocretin‐1 causes G protein activation and increases ACh release in rat pons

R Bernard, R Lydic… - European Journal of …, 2003 - Wiley Online Library
The effects of the arousal‐promoting peptide hypocretin on brain stem G protein activation
and ACh release were examined using 16 adult Sprague‐Dawley rats. In vitro [35S] GTPγS …

Long‐term enhancement of REM sleep by the pituitary adenylyl cyclase‐activating polypeptide (PACAP) in the pontine reticular formation of the rat

A Ahnaou, M Basille, B Gonzalez… - European Journal of …, 1999 - Wiley Online Library
In rats, rapid eye movement (REM) sleep can be elicited by microinjection of vasoactive
intestinal polypeptide (VIP) into the oral pontine reticular nucleus (PnO). In the present study …

Benzodiazepine receptor agonists cause drug-specific and state-specific alterations in EEG power and acetylcholine release in rat pontine reticular formation

VS Hambrecht-Wiedbusch, EA Gauthier… - Sleep, 2010 - academic.oup.com
Abstract Study Objectives: Benzodiazepine (BDZ) and non-benzodiazepine (NBDZ)
hypnotics enhance GABAergic transmission and are widely used for the treatment of …